Morphine

Question 1

Brand name of Morphine

Answer 1

Roxanol, M.S. Contin

Question 2

Drug class of Morphine

Answer 2

Opioid Analgesic

Question 3

What drug schedule is Morphine classified?

Answer 3

(Schedule II narcotic)

Question 4

Indications of Morphine

Answer 4

Severe CHF, acute pulmonary edema, chest pain associated with acute MI, analgesia for moderate to severe acute and chronic pain

Question 5

Morphine’s mechanism of action

Answer 5

Alleviates pain through CNS action. Suppresses fear and anxiety centers in the brain. Depresses brainstem respiratory centers. Increases peripheral venous capacitance and decreases venous return. Decreases preload and afterload, which decrease myocardial oxygen demand.

Question 6

Contraindication for Morphine

Answer 6

Head injury, exacerbated COPD, depressed respiratory drive, hypotension, undiagnosed abdominal pain, decreased LOC, suspected hypovolemia, patients who have taken MAOIs within 14 days.

Question 7

Adverse effects of Morphine

Answer 7

Confusion, sedation, headache, CNS depression, respiratory depression, apnea, bronchospasm, dyspnea, hypotension, syncope, bradycardia, tachycardia, NV, dry mouth.

Question 8

Precautions of Morphine

Answer 8

Potentiates sedative effects of phenothiazine’s
(promethazine) CNS depressants may
Potentiate effects, MAOI’s may cause
Paradoxical excitation

Question 9

Adult dose and admin of Morphine

Answer 9

STEMI 2-4 mg SIVP repeat dose 2-8 mg at 15 minute intervals. Pain control (medical direction).

Question 10

Pediatric dose and admin of Morphine

Answer 10

0.1-0.2 mg/kg IV/IO/IM/SC with max dose of 5 mg