The Other Glands Flashcards
The pancreas is both an ________ and ________ gland.
Endocrine
Exocrine
Where is the pancreas located? Physically describe it.
An elongated, spongy gland below and behind the stomach, mostly retroperitoneal
5” long, triangular in cross-section, weights 85-100 grams
What is the exocrine pancreas?
Consist of acini that produce digestive enzyme
What is the endocrine pancreas?
Clusters of different types of hormone-producing cells
What are the islets of Langerhans?
These islets contain anywhere from a few to 3,000 cells
What four cells do the islets of Langerhans produce?
Alpha cells (glucagon) Beta cells (insulin) Delta cells (pancreatic somatostatin) F-cells (pancreatic polypeptide)
What does an alpha cell produce?
Glucacon
Alpha cells are ____% of the islets of Langerhans while beta cells are ___%.
20%
70%
What does glucagon do?
Raise blood sugar level
How does glucagon raise blood sugar levels?
Targets liver to break down glycogen (to glucose) into the bloodstream, and via gluconeogenesis
What is gluconeogenisis?
Synthesis of glucose from lactic acid and other non-carbohydrate molecules
What does insulin do?
Lowers blood sugar level
After meals, _______ stimulates cells to absorb ________.
Insulin
Glucose
The liver uses insulin to make _______.
Glycogen
The brain, liver, and kidneys absorb and use glucose _______ of insulin levels, but insulin does promote the liver to make glycogen
regardless
What is a delta cell?
Pancreatic somatostatin
Delta cells make up ____% of the islets of Langerhans.
5-10%