The mechanics of breathing Flashcards
in terms of resistance to breathing what factors affect it? (2)
lung compliance
airway resistance
what’s lung compliance?
the ease with which the lungs can be expanded
what 3 factors affect lung compliance?
elasticity of lung tissue
mobility of chest wall
surface tension (of the alveoli)
what does elastic recoil oppose?
inspiration
what does elastic recoil aid?
expiration
when looking at a graph showing lung pressure during the respiratory cycle, what would it look like if there was no airway resistance?
no curve on the graph
how is compliance calculated?
change in volume (L)/ change in pressure cm H2O
what unit is compliance given in?
litres/cmH2O
what is the mobility of the thoracic cage?
the movement of the thoracic cage
what causes surface tension?
intermolecular forces between molecules in a liquid
what’s LaPlace’s law?
law describing the relationship between pressure (p), tension (T) and the radius of the alveolus (r)
according to LaPlace’s law, how is pressure (p) calculated?
p= 2T/r
how does pulmonary surfactant affect surface tension?
reduces it
what does a reduced surface tension mean for complicance?
it increases it
what does surfactant do to alveoli?
keeps uniform alveoli size
what is neonatal respiratory distress syndrome?
lack of surfactant secretion in premature babies, reducing compliance
causes alveoli collapse on exhalation and makes it difficult to inflate lungs
how many will die from neonatal respiratory distress syndrome without rapid treatment?
50%
does neonatal respiratory distress syndrome have a good or bad income with treatment?
good
what’s airway resistance?
major ‘non elastic’ source of resistance to gas flow
how does increasing resistance affected gas flow?
it reduces it
what is resistance mainly determined by?
radius
how is resistance affected along the journey of airflow (trachea–> terminal bronchiole)?
it reduces (even though it’s getting smaller, we have more of the tubes)
what 2 factors affect airway resistance?
lung volume
bronchial smooth muscle
what do the bronchi do as the lung expands?
dilate
as we grow up what happens to lung volume, therefore what happens to resistance?
it increases, therefore resistance reduces