The Gene and What it Does Test #4 Flashcards
Rosalind Franklin and Maurice Wilkins
Franklin performed technique X-Ray crystallography
nucleotide
monomers of DNA A:T C:G original strands called template free nucleotides found in cytoplasm & are made by the cell
telomeres/telomerase
telomeres: extra DNA on the ends of a chromosome that shorten each time DNA copies
short telomeres result in aging, death, cancer
Cells with active telomerase enzyme: STEM cells, cancers cells, embryo cells
DNA Replication
Occurs during S phase when DNA must be copied
Helicase
an enzyme that untwists the DNA
Weakens the bonds between bases (unzips the DNA)
DNA Polymerase
an enzyme that collects free floating nucleotides and links them together
gene
a region of DNA, whose bases code for one particular protein.
genetic code
the order or sequence of the nitrogenous bases
mRNA
(messenger) carries a copy of a gene from the cytoplasm to the ribosomes
Ribose
sugar used in RNA
Uracil
base matched to Adenine instead of thymine
rRNA
(ribosomal) used to make up the ribosome
helps make protein
tRNA
(transfer) carries amino acids to the ribosomes
RNA
ribose nucleic acid
single stranded
Transcription
Making RNA
Helicase enzyme separates the 2 strands
RNA polymerase collects free floating RNA nucleotide and like them to complementary bases (A:U, C:G)
when finished RNA breaks free and goes to cytoplasm and the DNA rezips and stays in the nucleus
codon
3 nitrogenous bases that code for one amino acid
64 different codons
20 different amino acids
translation
Decoding the message
happens in the cytoplasm of the cell
mRNA binds to the ribosome, the cell’s protein factory
start codons
aug or start codon on mRNA
carris the amino acid methionine
stop codon
carry no amino acids
uaa, uag, uga
mutation
alteration in gene code
mutant
an organism with an expressed mutation
mutagen
an environmental material that causes mutations
gene mutation
a mutation in one gene
frame shift
altering of nucleotide number that results in improper grouping of codons due to insert or delete nucleotides
exon
used for RNA and exit the ribosome
introns
removed and stay in nucleus
correction enzymes
repair mutations, remove incorrect nucleotides
RNA splicing
mRNA needs editing, like a rough draft
introns & extrons
Chromosomal mutations
duplication, insertion, inversion, translocation
duplication
regions of DNA are repeated
deletion
regions of chromosomes are lost
inversion
regions of chromosomes are reversed
translocation
region of one chromosome is move to a nonhomologous chromosome