The Blood Flashcards
How much of blood plasma is water
90%
How much of plasma proteins are albumin?
60%
Only what type of cells are complete cells?
WBC’S
What is globin composed of?
4 polypeptide chains (2 alpha, 2 beta)
What is heme responsible for?
Binds oxygen for preparation of transportation
What is the process of producing blood cells?
Hematopoiesis
What is in red bone marrow and what are they called?
Blood stem cells - hemapoietic stem cells
How long does erythropoiesis take?
15 days
What would reticulocyte tell you about what’s going on in the body?
Indicate a problem of impairment of blood production
Too many RBC leads to?
Increase blood viscosity
What is EPO?
Erythropoietin
What is EPO released by and in response to what
Kidneys in response to hypoxia
What are some causes of hypoxia?
- Hemorrhage
- Iron deficiency
- Reduced oxygen availability
What is the life span of mature erythropoietin?
100-120 days
What engulfs the dead erythrocytes and where ?
Macrophages and spleen
What are the three groups of anemia?
- Blood loss
- Low RBC production
- High RBC destruction
If you have too much leukocyte production, what is the infection called?
Leokocytosis
What are the two categories of leukocytes?
- Granulocytes
- Agranolocytes
What do granulocytes include?
- Neutrophils, eosinophils, basophils
What do agranulocytes include?
- Lymphocytes and monocytes
Which cells do lymphocytes contain?
WBC’s
How much of blood is erythrocytes?
45%
What is an abnormally low WBC called? How much?
Leukopenia and < 11,000
How can leukopenia be caused?
Drug induced
What are all cell fragments?
Platelets
What do platelets act in?
Megakaryocytes
What do megakaryoblast continue to do
Act in clotting process
What do megakaryoblast go through ( but nothing at other )
Mitosis at not cytokinesis
What is another name for blood clotting?
Hemostasis
Factors are what of clotting?
- Vascular spasm
- Platelet plug formation
- Coagulation
What are some homeostasis disorders ?
- Embolus
- Embolism
- thrombus
What is a thrombus?
Clot that develops and persist in an unbroken vessel
What is a embolus?
Thrombus freely floating in the bloodstream
What is an embolism?
Embolus obstructing a vessel
If someone is type AB , which antibodies do they have?
None
If someone is type o , which antibodies do they have?
Both a/b