Chapter 5 Flashcards
What is skin’s main function?
Protection
What is another name for skin?
Integument
What are the 2 distinct regions for the integument?
- Epidermis
- Dermis
What is the epidermis?
The superficial region
Epithelial tissue
What is the dermis?
Underlies epidermis
Mostly consist of connective tissue
Strong and flexible
What is the hypodermis?
- subcutaneous layer deep to the skin
- not part of the skin
- mostly muscles and adipose tissue
What are the 4 cells of the epidermis?
- Keratinocytes
- Melanocytes
- Dendritic cell
- Tactile cells
Keratinocytes
- Produce keratin - fibrous protein
- most cells of epidermis
- tightly connected by desmosomes
Melanocytes
- 10-25% of cells in deepest epidermis
- produce melanin → packaged into melanosomes → responsible for skin color
Dendritic cells (langerhans)
- Immune cell
- macrophages - key activators of immune system
Tactile cells (merkel)
- Sensory touch receptors
What are the layers of the epidermis (superficial to deep?)
- Stratum corneum
* stratum lucidium ( only in thick skin e.g. Palms of hand or soles of feet) - Stratum granulosum
- Stratum spinosum
- Stratum basale
Stratum basale
- Deepest epidermal layer
- actively mitotic:
• produces 2 daughter cells - melanocytes compose 10-25% of this layer
Stratum spinosum
- Aka prickly layer
- several layers thick
-Present melanosomes and dendritic cells
Stratum granlosum
- 4-6 cell layers
- keratinization begins
- cells apical to this layer die
Stratum lucidium
- Clear layer
- Only in thick skin
- few rows of dead keratinocytes
Stratum Corneum
- 20-30 rows of dead, flat, anuclecte, keratinized sacs
- although dead, functions to protect deeper cell
What are the two layers of the dermis?
- Papillary
- Reticular
What is the papillae layer composed of?
- areolar connective tissue
- collagen fibers
- elastic fibers
- blood vessels
What is the dermal papillae?
- peglike projections
What is a fingerprint ridge called?
Friction ridges
This layer is deep to the papillary layer.
Reticular layer
What composes the reticular layer?
- Dense fibrous connective tissue
- elastic fibers
- collagen filers
• cleavage line
What are the dark lines an our fingers and hands?
Flexure lines
What are stretch marks known as?
Striae ( silvery white scars)
In striae what does the stretching cause?
Dermal tears
What is a blister?
Fluid filled pocket that separates the dermis and epidermis
What are the 3 pigments that contribute to skin color?
- Melanin
- Carotene
- Hemoglobin
What color das hemoglobin give off?
Pinkish fair skin
What color does carotene give off? Where does it accumulate?
-Yellow to orange
- stratum corneum and hypodermis
What color does melanin give off?
- Reddish-yellow
- brownish - black
What can stimulate melanin production?
Sun exposure
If diagnosed with cyanosis, what color wold the skin be and why?
Blue and due to low oxygen of hemoglobin
If diagnosed with erythema, what color would the skin be and why?
Red and due to : fever, hypertension, inflammation, allergy
If diagnosed with jaundice, what color would the skin be and why?
Yellow and liver disorder
If I detected bruising on the skin, what is happening?
Clothed blood beneath the skin
If I detected the bronzing of someone’s skin , what would be the issue?
Inadequate steroid hormones in addison’s disease
What are the derivatives of the epidermis?
- Hairs and hair follicles
- Nails
- Sweat glands
- Sebaceous glands