tetracycline Flashcards
1
Q
name an example?
A
doxycycline
oxtetracycline
2
Q
indication for use
A
LRTI
acne vulgaris
rosacea -alterative treatment
chlamydia
Vacuum her bedroom Vibro chlorea acne rosacea Chlamydia Ureoplasma Ueolyxone Myco pneumoniae H pylori B- Lyme disease Ricketaaie See notes
3
Q
mechanism of action?
A
binds to 30S subunit
prevents elongation by interfering with binding of tTNRA to mRNA
4
Q
SE
A
nausea
vomiting
diarrhoea
hypersensitivity - rash, irritation, photosensitivity, intracranial hypertension
5
Q
contraindications
A
can impair development so should not be given in early childhood (< 12 y/o) and pregnancy
not to be given to those with renal impairment as it can increase plasma urea and decrease excretion.
6
Q
interactions
A
enhance effect of warfarin
not to be given within 2 hours of antacids, calcium, iron
