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LS antibiotics > quinolones > Flashcards

quinolones Flashcards

1
Q

name one

A

ciprofloxacin

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2
Q

what are its uses

A
  1. eye infections and corneal ulcers
  2. prevention of secondary menegitis
  3. dental infection- anthrax
  4. respiratory infections-psuenomas aeruginosa
  5. GI infections- travellers diarrhoea, shigella
  6. UTI
  7. cystitis
  8. prostatitis
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3
Q

MOA

A

inhibits DNA gyrase and therefore DNA synthesis

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4
Q

SE

A

headache, nausea, dizziness
GI upset
hypersensitivity reactions
increased risk of rupture of muscle tendon
prolonged QT interval
decreased seizure and hallucination threshold

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5
Q

CI

A

prolonged QT intervals/risk of arrhytmias
children - growing for example
seizures/epileptic

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6
Q

DI

A

NSAID- increase risk of seizures
prednisolone increases risk of muscle tendon rupture
theophylline increased risk of convulsions and ciclosprin increased risk of nephrotoxicity

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LS antibiotics (14 decks)

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