glycopeptide Flashcards
1
Q
name an example
A
vancomycin
2
Q
uses of vancomycin
A
1 ) gram pos infections such as endocarditis, osteomyeloitis where pencillin cannot be given due to allergy or resistence
2) propylaxis measure for MRSA
3) C diffcle colitis were metronidazole is poorly tolerated
3
Q
MOA
A
inhibits cell wall synthesis by preventing cross linking of peptiglycans
4
Q
AE
A
pain and inflammation at vein site- thrombophlebitis
red man syndrome
IV- nephrotoxicity and otoxocity
neutropenia and thrombocytopenia
5
Q
what is red man syndrome?
A
erythema
hypotension
bronchospasm
6
Q
interactions?
A
increase oto and nephrotoxicity with
aminoglycosides
diuetrics
ciclopsorin
DAC/CAD
7
Q
contraindicated?
A
elderly
renal impairment
those with history of deafness
8
Q
another use ?
A
peritonitis associated with peritoneal dialysis
