Cephalosporin Flashcards

1
Q

Uses

A
Respiratory tract infection 
Otitis media 
Uti 
Surgical prophylaxis 
Pneumonia 
Septicaemia 
Meningitis
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2
Q

MoA

A

Beta lactam group

Inhibit cel wall peptiglycan linking

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3
Q

Drugs classes

How to remember first gen

A

PH FAD FAZ

Second gen a key one is cefuroxime
Third gen ceftriazone

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4
Q

Which can be used in allergy

A

Second gen and third with caution

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5
Q

Ae

A
dDt hap(e)ns
Diarrhoea, disulfram reaction, thrombophlebitis , hypoprothrombeniema , allergy/hypsensitvity ,  nephrotoxicity , super infections
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6
Q

CI

A

Hypersensivity reaction
C. difficile risk
Renal impairment

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7
Q

Di

A

Warfarin due to p450 inhibition the

Amonpgrlycoside nephrotoxicity

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