nitrofurotoin Flashcards

1
Q

use

A

UTI first line

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2
Q

MOA

A

metabolised by enzyme in bacteraia where the active metabolite damages bacterial DNA and causes cell death
both gram neg and pos

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3
Q

AE

A
rash, hypersensitivity 
gi upset 
dark yellow brown urine 
pulkmonary reaction 
false urinary glucose
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4
Q

CI

A
pregnancy 
acute porphyria
G6PDdeficency 
diabetes
vitb12 deficiency 
anaemia
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5
Q

DI

A

none but ca take with milk or food to reduce gi symptoms

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