metronidazole Flashcards
1
Q
uses
A
anaerobes
2nd line or third line for c.difficle
giardiasis, aemobic dysentery
h.pylori
2
Q
MOA
A
when reduced form, it works by producing a nitro free radial which intefers with DNA production and causes DNA degradation
3
Q
SE
A
Metallic taste, thrombophelitis, rash/hypersensitivity, nausea and vomiting, drug eruptions, itching, neuropathy
vertigo
4
Q
CI
A
hhyperesentivity a liver disease alcohol
5
Q
drugs interactions
A
alcohol
inhibition of p450 enzyme
increase lithium toxicity
phentoyin and rimpiacin decrease abx efficacy
