Terminal Respiration Flashcards
Only site of oxidative phosphorylation
Mitochondria
____ and ____ must be in the mitochondrial matrix fro terminal respiration to take place
NADH and FADH2
Where is the majority of NADH and FADH2 formed
Citric acid cycle and B-oxidation of fatty acids
Glycerol Phosphate Shuttle
Cytoplasmic NADH cannot cross mitochondrial membrane but FADH2 can pass on its electrons using G3P
Electron Transport Chain Enzymes
Complex I
Complex II
Complex III
Complex IV
Complex I
Redox reaction using NADH
Ubiquinone (Q) is reduced to Ubiquinol (QH2)
Transfer of electrons and movement pumps H+ into intermembrane space
Complex II
No H+ pumps
FADH2 is oxidised Q-QH2
Iron sulphur centres trap electrons
Complex III
Takes electrons from ubiquinol (QH2) and passes them to Cytochrome C
Pumps protons into inter-membranous space
Complex IV
Takes electrons from cytochrome C to Oxygen to form H20
Chemiosmosis
as electrons move through the transport chain protons are pumped to intermembranous space
Proton motive force
protons are allowed to flow back in down their concentration gradient
How is ATP created using proton motive force
Protons flow through ATP synthase and this energy is used to convert ADP +P to ATP
ATP has 2 parts:
F0- membrane bound
F1- protrudes into the mitochondrial matrix and acts as a catalyst
Process of ATP formation
binding-change mechanism
Binding Change Mechanims
O = open = new ATP relelased and ADP + P bind L = loose = bound ADP + P cannot be released T = Tight = condensation of ADP + P to form ATP
