Introduction to Blood Flashcards

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1
Q

How many litres of blood in the human body

A

5L

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2
Q

Where are the 5L of blood contained

A

3/5 Venous
1/5 Arterial
1/5 Lung

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3
Q

Functions of blood (6)

A
Transport of nutrients, hormones, waste
Clotting
Defence
Carrier of gas
Thermoregulation
Maintenance of ECF
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4
Q

Composition of blood

A

Plasma, RBC, WBC

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5
Q

Plasma Proteins

A

Albumin
Globulin
Fibrinogen

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6
Q

Albumin

A

Most abundant
Binds to drugs like warfarin
Binds to steroid hormones and lipids
Create colloid oncotic pressure

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7
Q

Globulin

A

alpha, beta, gamma
Prevent transport molecules being lost in the urine
Transport proteins, lipids and fat-soluble vitamins

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8
Q

Fibrinogen

A

Clotting factor

Remain within circulation

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9
Q

Colloid oncotic pressure

A

Creates force that pulls water from the interstitial space to the vessel lumen

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10
Q

Capillary Hydrostatic pressure

A

favours movement outside of capillaries

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11
Q

Hyperproteinaemia

A

Decrease in plasma protein
Starvation due to decreased protein intake
Plasma protein cannot be synthesised in liver
Kidney disease
Malabsorption
Oedema- loss of oncotic pressure

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12
Q

Process of synthesising erythrocytes (RBCs)

A

Erythropoiesis

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13
Q

Erythropoietin is synthesised by the_____ and is a _____

A

Kidney and a hormone involved in erythropoiesis

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14
Q

Leukocytes

A

Neutrophils (most abundant)
Basophils
Eosinophils
Monocytes (connective tissue - macrophages)

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15
Q

Formation of leukocytes

A

leukopoiesis

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16
Q

Bacterial infection produces___

A

neutrophils

17
Q

Viral infection produces____

A

Lymphocytes

18
Q

How are platelets formed

A

using thrombopoietin and are fragmented from megakaryocytes

19
Q

Function of platelets

A

Stick to damaged endothelial gaps which initiates clotting

20
Q

Haematocrit

A

how many RBC as a percentage of total blood volume

21
Q

Bilirubin

A

breakdown product of RBC- gives plasma a yellow colour