Introduction to Blood Flashcards
How many litres of blood in the human body
5L
Where are the 5L of blood contained
3/5 Venous
1/5 Arterial
1/5 Lung
Functions of blood (6)
Transport of nutrients, hormones, waste Clotting Defence Carrier of gas Thermoregulation Maintenance of ECF
Composition of blood
Plasma, RBC, WBC
Plasma Proteins
Albumin
Globulin
Fibrinogen
Albumin
Most abundant
Binds to drugs like warfarin
Binds to steroid hormones and lipids
Create colloid oncotic pressure
Globulin
alpha, beta, gamma
Prevent transport molecules being lost in the urine
Transport proteins, lipids and fat-soluble vitamins
Fibrinogen
Clotting factor
Remain within circulation
Colloid oncotic pressure
Creates force that pulls water from the interstitial space to the vessel lumen
Capillary Hydrostatic pressure
favours movement outside of capillaries
Hyperproteinaemia
Decrease in plasma protein
Starvation due to decreased protein intake
Plasma protein cannot be synthesised in liver
Kidney disease
Malabsorption
Oedema- loss of oncotic pressure
Process of synthesising erythrocytes (RBCs)
Erythropoiesis
Erythropoietin is synthesised by the_____ and is a _____
Kidney and a hormone involved in erythropoiesis
Leukocytes
Neutrophils (most abundant)
Basophils
Eosinophils
Monocytes (connective tissue - macrophages)
Formation of leukocytes
leukopoiesis