teratogens

Question 1

renal damage

Answer 1

ace inhibitors

Question 2

absence of digits/multiple anomalies

Answer 2

alkylating agents

Question 3

CN VIII toxicity

Answer 3

aminoglycosides

Question 4

facial dsymorphism, developmental delay, neural tube defects, phalanx/fingernail hypoplasia

Answer 4

carbamazepine

Question 5

vaginal clear cell adenocarcinoma, congenital mullerian anomalies

Answer 5

DES

Question 6

neural tube defects

Answer 6

folate antagonists

Question 7

multiple severe birth defects

Answer 7

isotretinoin

Question 8

atrialized right ventricle

Answer 8

lithium

Question 9

aplasia cutis congenita

Answer 9

methimazole

Question 10

fetal hydantoin syndrome - cleft palate, cardiac defects, phalanx/fingernail hypoplasia

Answer 10

phenytoin

Question 11

discolored teeth

Answer 11

tetracyclines

Question 12

limb defects - phocomelia, micromelia, flipper limbs

Answer 12

thalidomide

Question 13

inhibition of maternal folate absorption leading to neural tube defects

Answer 13

valproate

Question 14

bone deformities, fetal hemorrhage, abortion, opthalmologic abnormalities

Answer 14

warfarin

Question 15

placental abruption

Answer 15

cocaine

Question 16

IUGR, ADHD, preterm labor, placental problems, low birth weight

Answer 16

smoking, nicotine

Question 17

nicotine causes what

Answer 17

vasoconstriction

Question 18

extremely high risk for spontaneous abortions and birth defects such as cleft palate and cardiac defects

Answer 18

vit a excess

Question 19

microcephaly, intellectual disability

Answer 19

xrays

Question 20

when are u most susceptible to teratogens

Answer 20

week 3-8