Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

STEP 1 > Biochem - metabolism :) > Flashcards

Biochem - metabolism :) Flashcards

1
Q

Rate determining step: glycolysis

A

PFK-1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Rate determining step: Gluconeogenesis

A

fructose-1,6-bisphosphatase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Rate determining step: TCA cycle

A

isocitrate dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Rate determining step: glyogenesis

A

glycogen synthase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Rate determining step: glycogenolysis

A

glycogen phosphorylase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Rate determining step: HMP shunt

A

glucose-6-phosphate dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Rate determining step: de novo pyrimadine synthesis

A

carbamoyl phosphate synthetase II (CPS2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Rate determining step: de novo purine synthesis

A

glutamine PRPP amidotransferase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Rate determining step: Urea cycle

A

carbamoyl phosphate synthetase I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Rate determining step: fatty acid synthesis

A

acetyl coa carboxylase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Rate determining step: Fatty acid oxidation

A

Carnitine acyltransferase I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Rate determining step: Ketogenesis

A

HMG CoA synthase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Rate determining step: Cholesterol synthesis

A

HMG CoA reductase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Gibbs free energy equation

A

delta G = deltaH - TdeltaS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Drugs that inhibit complex I

A

rotenone
mPP
amytal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Drugs that inhibit complex III

A

antimycin A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Things that inhibit complex IV

A

CO
cyanide
sodium azide (N3-)
H2S

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Things that inhibit atp synthase (complex V)

A

oligomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

4 sites of HMP shunt existence

A

1) rbcs
2) mammary glands
3) liver
4) adrenal cortex

20
Q

fructokinase deficiency causes

A

essential fructosuria (not a big deal)

21
Q

aldolase B deficiency causes

A

fructose intolerance (bad)

22
Q

Rx for fructose intolerance

A

decrease intake of fructose and sucrose

23
Q

galactokinase deficiency

A

relatively mild, only symptom is infantile cataracts, maybe some failure to track objects/lack of social smile.

24
Q

absence of galactose 1 phosphate uridyltransferase

A

classic galactosemia
failure to thrive, jaundice, hepatomegaly, infantile catarcats, disability, E coli sepsis in neonates = severe symptoms soon after starting feeding

25
Q

Rx classic galactosemia

A

exclude galactose and lactose in diet

26
Q

lack of what enzyme can lead to sorbitol induced osmotic damage

A

sorbitol dehydrogenase

27
Q

what cells lack sorbitol dehydrogenase

A

lens, schwann cells, retina, kidneys

28
Q

acidic amino acids

A

aspartic acid and glutamic acid

negative at body pH

29
Q

basic amino acids

A

arginine, lysine, histidine

positive at body pH except histidine =no charge

30
Q

essential amino acids

A

PVT TIM HaLL

phenylalanine
valine
threonine
tryptophan
isoleucine
lysine
histidine
leucine
lysine
31
Q

ketogenic amino acids

A

leucine and lysine

32
Q

fatty acid oxidation (beta oxidation) location

A

mitochondria

33
Q

glycolysis location

A

cytosol

34
Q

acetyl-coa production location

A

mitochondria

35
Q

heme synthesis location

A

mitochondria and cytosol

36
Q

tca cycle location

A

mitchondria

37
Q

fatty acid synthesis location

A

cytosol

38
Q

urea cycle location

A

both mitochondria and cytosol

39
Q

oxidative phosphorylation location

A

mitochondria

40
Q

gluconeogenesis location

A

both mitochondria and cytosol

41
Q

HMP shunt location

A

cytoplasm

42
Q

protein syntehsis (RER) loctaion

A

cytoplasm

43
Q

ketogenesis location

A

mitochondria

44
Q

cholesterol syntehsis

A

cytoplasm

45
Q

steroid synthesis location

A

cytoplasm

STEP 1 (26 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions