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STEP 1 > ovarian neoplasms > Flashcards

ovarian neoplasms Flashcards

1
Q

most common type of ovarian tumor

A

surface epithelial tumor

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2
Q

BRCA1 mutation carriers have an increased risk of what type of cancer

A

serous carcinoma of ovary and fallopian tube

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3
Q

tumor composed of bladder-like epithelium (uroepithelium)

A

Brenner

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4
Q

are brenner tumors malignant or benign usually?

A

benign

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5
Q

tumor composed of endometrial-like glands

A

endometrioid tumor

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6
Q

are endometrioid tumors usually benign or malignant?

A

malignant

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7
Q

what is important to check after a diagnosis of ovarian endometrioid tumor?

A

check for endometrial carcinoma in uterus

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8
Q

single cyst with simple, flat lining

A

cystadenoma

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9
Q

tumor arising in premenopausal woman, 30-40 years

A

cystadenoma

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10
Q

CA-125 is only useful to monitor what type of ovarian tumors

A

surface epithlial tumors

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11
Q

how is prognosis of surface epithelial tumors

A

poor- worst prognosis of female genital tract cancers

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12
Q

second most common type of ovarian tumor

A

germ cell tumor

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13
Q

what age group do germ cell tumors occur

A

reproductive age

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14
Q

what age group do malignant surface epithelial tumors occur

A

older - 60-70

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15
Q

most common germ cell tumor

A

cystic teratoma

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16
Q

cystic tumor composed of fetal tissue derived from two or three embryological layers

A

cystic teratoma

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17
Q

are cystic teratomas benign or malignant

A

benign, but can have malignant potential if there is immature embryonic material present or somatic malignancy

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18
Q

what is the most common immature tissue found in a cystic teratoma

A

neural tissue

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19
Q

what is the most common somatic malignancy associated with cystic teratoma

A

squamous cell carcinoma of skin

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20
Q

what is a struma ovarii

A

cystic teratoma composed of primarily thyroid tissue

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21
Q

hyperthyroidism plus a mass in adnexal region

A

struma ovarii

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22
Q

what is the most common malignant germ cell tumor

A

dysgerminoma

23
Q

tumor composed of large cells with clear cytoplasm and central nuclei

A

dysgerminoma

24
Q

what is the testicular counterpart of dysgerminoma

A

seminoma

25
Q

what is the prognosis and treatment of dysgerminoma

A

good prognosis, treated with radiotherapy

26
Q

what marker is increased with dysgerminoma

A

LDH

27
Q

endodermal sinus tumor is what kind of tumor

A

yolk sac tumor (germ cell)

28
Q

most common germ cell tumor in children

A

endodermal sinus tumor (yolk sac)

29
Q

5 yo girl with ovarian mass

A

endodermal sinus tumor

30
Q

serum AFP is increased with this type of tumor

A

endodermal sinus tumor

31
Q

schiller duvall body

A

endodermal sinus tumor

32
Q

biopsy reveals glomeruloid like structures

A

schiller duvall body, associated with endodermal sinus tumor

33
Q

malignant tumor composed of cytotrophoblast and syncytiotrophoblasts

A

choriocarcinoma

34
Q

small, hemorrhagic tumor

A

choriocarcinoma

35
Q

what marker is raised in choriocarcinoma

A

beta-HCG

36
Q

where is beta hcg secreted from

A

syncytiotrophoblast

37
Q

high beta-hcg can lead to what

A

thecal cysts in ovary

38
Q

what part of normal placenta is absent in choriocarcinoma

A

villi

39
Q

how does choriocarcinoma respond to chemo

A

poorly - heamtogenous spread very early on

40
Q

malignant tumor composed of large primitive cells

A

embryonal carcinoma

41
Q

granulosa-theca cell tumors secrete what

A

estrogen

42
Q

prognosis of embryonal carcinoma

A

aggressive and metastasizes early

43
Q

is granulosa theca cell malignant or benign

A

malignant but rarely metastasizes

44
Q

reinke crystals

A

sertoli-leydig tumor

45
Q

sertoli leydig cells can secrete what

A

androgens

46
Q

presents with estrogen excess

A

granulosa-theca

47
Q

presents with androgen excess

A

sertoli-leydig

48
Q

pleural effusions and ascites plus ovarian tumor

A

meigs syndrome - fibroma

49
Q

benign tumor of fibroblasts

A

fibroma

50
Q

treatment of meigs syndrome

A

resolves with removal of tumor

51
Q

mucinous cystadenocarcinoma bilateral or unilateral

A

usually unilateral

52
Q

krukenberg

A

metastatic mucinous tumor, bilateral

53
Q

massive amounts of mucus in peritoneum

A

psuedomyxoma peritonei

54
Q

pseudomyxoma peritonii is due to mucinous tumor located where

A

appendix that metastasizes to ovary

STEP 1 (26 decks)

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