bone tumors Flashcards
osteoma is a tumor of what
bone
osteomas most commonly occur
surface of facial bones
osteomas are associated with what syndrome
gardner syndrome (FAP)
osteoid osteomas are benign tumors of what
osteoblasts
what part of bone do osteoid osteomas occur
cortex of long bones (femur)
bone pain that resolves with aspirin
osteoid osteoma
osteoblastomas occur in what bones
vertebrae
bone pain that does not resolve with aspirin
osteoblastoma
bony mass
osteoid osteoma
bony mass > 2cm with a radiolucent core
osteoblastoma
most common benign of tumor of bone
osteochondroma
tumor of bone with an overlying cartilage cap
osteochondroma
lateral projection of growth plate (metaphysis)
osteochondroma
osteochondromas can rarely transform to what tumor
chondrosarcoma
where do osteosarcomas occur
metaphysis of long bones
incidence of osteosarcomas (age range and risk factors)
most prevalent = children (Rb gene)
elderly: pagets and radiation exposure
sunburst on xray
osteosacroma
codman triangle
osteosarcoma
pleomorphic cells that produce osteoid
osteosarcoma
osteosarcomas are malignant proliferation of what cells
osteoblasts
multinucleated giant cells and stromal cells
giant cell tumor
giant cell tumors occur in what part of the bone
epiphysis
soup bubble appearance
giant cell tumor
locations of giant cell tumors
distal femur / proximal tibia (knee)
ewing sarcoma cells are derived from what origin
neuroectoderm
what two tumors arise in diaphysis
ewing sarcoma
osteoid osteoma
what part of bone does ewing sarcoma occur in
diaphysis
small round blue cells
ewing sarcoma
what bone tumors occur in males
osteochondroma
what bone tumors occur boys
ewing sarcoma
onion skin periosteal reaction on xray
ewing sarcoma
what tranaslocation occurs in ewing sarcoma
11,22
what fusion protein does the 11,22 translocatio make
EWS-FL I
benign tumor arising in the medulla of the small hands and feet
chondroma
where do chondrosarcomas occur
medulla of pelvis or central skeleton
most metastatic tumors create what type of lsions
lytic punched out
prostatic tumors create what lesions
osteoblastic