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STEP 1 > bone tumors > Flashcards

bone tumors Flashcards

1
Q

osteoma is a tumor of what

A

bone

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2
Q

osteomas most commonly occur

A

surface of facial bones

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3
Q

osteomas are associated with what syndrome

A

gardner syndrome (FAP)

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4
Q

osteoid osteomas are benign tumors of what

A

osteoblasts

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5
Q

what part of bone do osteoid osteomas occur

A

cortex of long bones (femur)

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6
Q

bone pain that resolves with aspirin

A

osteoid osteoma

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7
Q

osteoblastomas occur in what bones

A

vertebrae

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8
Q

bone pain that does not resolve with aspirin

A

osteoblastoma

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9
Q

bony mass

A

osteoid osteoma

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10
Q

bony mass > 2cm with a radiolucent core

A

osteoblastoma

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11
Q

most common benign of tumor of bone

A

osteochondroma

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12
Q

tumor of bone with an overlying cartilage cap

A

osteochondroma

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13
Q

lateral projection of growth plate (metaphysis)

A

osteochondroma

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14
Q

osteochondromas can rarely transform to what tumor

A

chondrosarcoma

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15
Q

where do osteosarcomas occur

A

metaphysis of long bones

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16
Q

incidence of osteosarcomas (age range and risk factors)

A

most prevalent = children (Rb gene)

elderly: pagets and radiation exposure

17
Q

sunburst on xray

A

osteosacroma

18
Q

codman triangle

A

osteosarcoma

19
Q

pleomorphic cells that produce osteoid

A

osteosarcoma

20
Q

osteosarcomas are malignant proliferation of what cells

A

osteoblasts

21
Q

multinucleated giant cells and stromal cells

A

giant cell tumor

22
Q

giant cell tumors occur in what part of the bone

A

epiphysis

23
Q

soup bubble appearance

A

giant cell tumor

24
Q

locations of giant cell tumors

A

distal femur / proximal tibia (knee)

25
Q

ewing sarcoma cells are derived from what origin

A

neuroectoderm

26
Q

what two tumors arise in diaphysis

A

ewing sarcoma

osteoid osteoma

27
Q

what part of bone does ewing sarcoma occur in

A

diaphysis

28
Q

small round blue cells

A

ewing sarcoma

29
Q

what bone tumors occur in males

A

osteochondroma

30
Q

what bone tumors occur boys

A

ewing sarcoma

31
Q

onion skin periosteal reaction on xray

A

ewing sarcoma

32
Q

what tranaslocation occurs in ewing sarcoma

A

11,22

33
Q

what fusion protein does the 11,22 translocatio make

A

EWS-FL I

34
Q

benign tumor arising in the medulla of the small hands and feet

A

chondroma

35
Q

where do chondrosarcomas occur

A

medulla of pelvis or central skeleton

36
Q

most metastatic tumors create what type of lsions

A

lytic punched out

37
Q

prostatic tumors create what lesions

A

osteoblastic

STEP 1 (26 decks)

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