FA pharm Flashcards

1
Q

volume of distribution

A

amt of drug given (IV) / drug concentration in plasma

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2
Q

drug clearance

A

0.7 x Vd / halflife

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3
Q

loading dose

A

Css x Vd

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4
Q

maintenance dose

A

Css x CL

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5
Q

examples of zero order kinetics

A

PEA:

phenytoin, ethanol, aspirin

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6
Q

weak acids and how to treat

A

phenobarbital, methotrexate, aspirin

rx: bicarbonate

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7
Q

weak base and how to treat

A

amphetamines

rx: ammonium chloride

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