repro Flashcards
ovaries lymph drainage
para aortic
testes lymph drainage
para aortic
vagina lymph drainage
superficial inguinal
vulva lymph drainage
superficial inguinal
scrotum lymph drainage
superficial inguinal
proximal vagina lymph drainage
obturator/external iliac/hypogastric
uterus lymph drainage
obturator/external iliac/hypogastric
what ligament contains ovarian vessels
suspensory ligament (infundibulopelvic)
what ligament contains uterine vessels
cardinal ligament
what vessels are ligated during oopherectomy
ovarian vessels, contained in the suspensory ligament
what ligament contains the ovaries, fallopian tubes, and the round ligament of uterus
broad ligament
what ligament is a derivative of gubernaculum?
round ligament and ovarian ligament
what ligament connects labia majora to uterine fundus
round ligament
most common area for cervical cancer
squamocolumnar junction (transition zone)`
membranous urethra is prone to injury from what
pelvic fracture
bulbar urethra is prone to injury from what
blunt force
injury of the posterior urethra can cause urine to leak where
retropubic space
what part of urethra is at risk of injury due to a straddle injury
anterior urethra
if anterior urethra is injured, where will urine leak
beneath buck fascia (deep)
if buck fascia is torn and there is urethral injury, where will urine leak
superficial perineal space
what nerve causes erection
pelvic nerve
what nerve causes penile emmision
hypogastric
what nerve causes ejaculation
pudendal nerve
remnant of mesonephric duct in females
gartner duct
incomplete fusion of them mullerian ducts
bicornuate uterus
complete failure of fusion
double uterus/vagina/cervic - pregnancy IS possible
females with mullerian defects should undergo ultrasound to see if they have what abnormalities?
urologic (renal)
failure of urethral folds to fuse
hypospadias
faulty positioning of the genital tubercle
epispadias
epispadias is associated with what other abnormality
bladder exstrophy
hypospadias is associated with what other abnormliaties
inguinal hernia, cryptorchidism
how do estrogen receptors work
expressed in cytoplasm and translocate to nucleus when bound by estrogen
how does estrogen affect myometrial excitability
increases
what enzyme does LH stimulate in females to produce estrogen
desmolase (produces androgens in theca cell from cholesterol)
what hormone increases basal body temperature
progesterone
precocious puberty is the development of sex characteristics before age what
7
oligomenorrhea is a cycle how long
> 35 days
polymenorrhea is a cycle how long
how long is luteal phase
14 days
how long is follicular phase
varies
what defines menorrhagia
heavy menstrual bleeding > 80 mL or >7 days
ovulation occurs when
14 days before menses always
what week does gastrulation occur
3
what weeks are organogenesis
weeks 3-8, embryonic period
when does the neural tube close by
week 4
when do the upper and lower limb buds form
week 4
when is fetal cardiac activity visible by transvaginal ultrasound
week 6
when does the heart start to beat
week 4
when can you sense fetal movement
week 8
when does the fetus have male/female characteristics
week 10
what is gastrulation
formation of trilaminar disc
leading cause of intellectual disability in US
fetal alcohol syndrome
mechanism of abnormalities in fetal alcohol syndrome
abnormal cell migration
what secretes bhCG
snycytiotrophoblast
dizygotic twins are always what
dichorionic and diamnionic
twins that split between 0-4 days will be
dichorionic and diamnionic
twins that split between 4-8 days
monochorionic and diamnionic
twins that split between 8-12 days
monochorionic and diamnionic
twins that split >13 days
conjoined; monochorionic and monoamnionic
conjoined twins are most likely to be joined where
chest
what stimulates corpus luteum to make progesterone in first trimester
beta HCG from syncytiotrophoblast
syncytiotrophoblast lacks what to decrease attach by maternal immune system
MHC I
what is the maternal part of placenta known as
decidua basalis
umblical arteries and vein are derived from what
allantois
urine discharge from umbilicus
failure of urachus to obliterate (patent urachus)
urachus attaches what
umblicus to bladder
urachal cysts can progress to what
infection and adenocarcinoma
what week does the urachus turn into allantois
3
what week does the vitelline duct obliterate
7
vitelline duct connets what
yolk sac to midgut lumen
meconium discharge from umblicus
vitelline fistula
maxillary artery is a branch of what
external carotid
1st aortic arch becomes
maxillary artery
2nd aortic arch becomes
stapedial and hyoid arteries
3rd aortic arch becomes
common carotid and proximal part of internal carotid
4th aortic arch becomes
left: aortic arch
right: subclavian artery
5th aortic arch becomes:
degraded
6th aortic arch becomes
pulmonary arteries and on the left, ductus arteriosus
branchial cleft/grooves are derived from
ectoderm
branchial arches are derived from
mesoderm and neural crest
branchial pouches are derived from
endoderm
first branchial cleft becomes
external auditory meatus
2nd through 4th clefts become
temporary cervical sinuses, obliterated by proliferation of 2nd arch mesenchyme
how does a persistent cervical sinus present
branchial cleft cyst within lateral neck
polyhydramnios is how much amniotic fluid
1.5-2 or more
oligohydramnios is how much amnionic fluid
most common gynecological cancer worldwide
cervical
most to least common gynecological cancer in US
endometrial > ovarian > cervical
prognosis worst to best of gynecological cancer
ovarian > cervical > endometrial
cancer from lower 1/3 of vagina spreads to what lymph nodes
inguinal
cancer form upper 2/3 of vagina spreads to what lymph nodes
regional iliac nodes
embryonal rhabdomyosarcoma stain for what two immunohistochemicals
desmin and myogenin
most common ovarian mass in young women
follicular cyst
drug for prostate cancer and MOA
flutamide - nonsteroidal competitive inhibitor at androgen receptor
drug for endometriosis
danazol
danazol MOA
partial agonist at androgen and progesterone receptors (decreases LH and FSH)
danazol side effects
hirsutism, virilazation (androgenic side effects)
finasteride MOA
5 alpha reductase inhibitor
anastrazole/exemestane MOA
aromatase inhibitors used in postmenopausal women with ER positive breast cancer
side effects of tamoxifen
increased risk of thromboembolic events and endometrial cancer