Surfactant and compliance Flashcards
role of pulmonary surfactant
reduces surface tension on alveolar surface membrane thus reducing tendency for alveoli to collapse (recoil)
law of Laplace
pressure required to keep an alveoli open is equal to 2T/r (so surfactants are more effective on smaller alveoli)
compliance
change in volume relative to change in pressure (stretchability of lungs)
factors that affect compliance
action of surfactant, ageing, disease
surfactant is
detergent like fluid produced by type II alveolar cells
surface tension
attraction between water molecules that occurs when ever there is an air water interface
high compliance
large increase in lung volume for small decrease in ip pressure
low compliance
small increase in lung volume for large decrease in ip pressure
compliance is determined by
elastic forces, surface tension at the alveolar air liquid interface and by airway resistance