pathology of pulmonary infection Flashcards
lung infections may be outcome of
microorganism pathogenicity, capacity to resist infection and population at risk
examples of respiratory tract defence mechanisms
general immune system, respiratory tract secretions, upper respiratory tract acts as a filter
macrophage mucociliary escalator system involves
alveolar macrophages getting on to mucociliary escalator which is going out of the lung and cough reflex
effects that lower respiratory tract infections can have
cytopathic effect of viral infection, damaging epithelial cells and losing function of mucociliary escalator. chronic bronchiolitis,
pneumonia can be classified
anatomically, aetiologically, microbiologically
types of pneumonia
community acquired, hospital acquired, in immunocompromised, atypical, aspiration, recurrent
bronchopneumonia
both lungs, usually lower lobes, common in copd patients, focal problem centred on small airways,
lobar pneumonia
effects a lobe, inflammatory reaction to the infectory organism, causes consolidation
outcomes of pneumonia
resolve, pleurisy, pleural effusion, empyema, organisation (lump), lung abscess, bronchiectasis,
when can a lung abscess develop
if there is a tumour, aspiration, particular organisms eg staph aureus, metastatic in pyaemia, can be a secondary infection of necrotic lung tissue
bronchiectasis is
pathological dilation of bronchi
bronchiectasis is caused by
severe infective episodes, recurrent infections, proximal bronchial obstruction, lung parenchymal destruction
aspiration pneumonia can be due to
food into lungs-
vomiting, oesophageal lesion, obstetric anaesthesia on full stomach, neuromuscular disorders eg gag reflex loss of function, sedation