Control of ventilation- chemoreceptors Flashcards
how respiratory motor movements are affected by the CNS
nerves act on skeletal muscle and contract for inspiration and relax for expiration. they reside in ill defined centres located in the pons and medulla. subconscious. dependent on signalling from brain
two classes of chemoreceptors
central and peripheral
nerves that act on external intercostal muscles
intercostal
how do peripheral chemoreceptors become important during hypoxia
respond to changes in oxygen partial pressure so are critical during hypoxia
dorsal respiratory group works on
inspiratory muscles via phrenic and intercostal muscles
ventral respiratory group works on
tongue, pharynx, larynx, expiratory
central chemoreceptors
found in medulla, respond to hydrogen ions, give primary ventilatory drive
peripheral chemoreceptors
found in carotid and aortic bodies, respond to PO2 and plasma, secondary ventilatory drive
increased partial pressure of carbon dioxide in blood is called
hypercapnea
central chemoreceptors
found in medulla, respond to hydrogen ions and PCO2 in plasma, give primary ventilatory drive
how does CO2 affect acid-base balance
broken down into bicarbonate and hydrogen which leaves hydrogen ions which alter pH
how can respiratory system create acid base disturbances
if you start off with normal resting level of hydrogen ion levels in plasma and this changes to abnormal levels by hyper or hypo ventilation
how can respiratory system compensate for acid base disturbances
if plasma pH falls then ventilation will be stimulated, if plasma pH increases then ventilation will be inhibited
pH is proportional to
bicarbonate over carbon dioxide