Sugammadex Flashcards
Unlike neostigmine, sugammadex does not require co-administration of which type of agent to avoid adverse cholinergic effects?
A) Antimuscarinic agents
B) Anticholinesterase inhibitors
C) Sympathomimetics
D) Beta-blockers
A) Antimuscarinic agents
like atropine or glycopyrrolate
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Why might sugammadex have fewer adverse effects compared to traditional reversal agents?
A) It crosses the blood-brain barrier.
B) It produces acetylcholine.
C) It does not produce cholinergic side effects.
D) It activates muscarinic receptors.
C) It does not produce cholinergic side effects.
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What is one major adverse effect of sugammadex in susceptible individuals?
A) Increased heart rate
B) Malignant hyperthermia
C) Prolonged duration of action in patients with renal impairment
D) Sudden hypotension
B) Malignant hyperthermia
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Sugammadex may be dangerous in certain circumstances due to its potential to increase:
A) Plasma glucose concentration
B) Plasma potassium concentration
C) Plasma calcium concentration
D) Plasma sodium concentration
B) Plasma potassium concentration
Can cause hyperkalemia
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What is the primary function of Sugammadex?
A) It inhibits acetylcholinesterase.
B) It surrounds rocuronium, rendering it inactive.
C) It blocks the release of acetylcholine.
D) It prevents potassium concentration changes.
B) It surrounds rocuronium, rendering it inactive.
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Sugammadex has been shown to work with which of the following neuromuscular blocking agents? (Select all that apply)
A) Vecuronium
B) Pancuronium
C) Atracurium
D) Rocuronium
A) Vecuronium
B) Pancuronium
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Match the following types of neuromuscular blockade reversal with their corresponding sugammadex dosage:
Shallow/Medium Blockade
Deep Blockade
Immediate Reversal (3 minutes after 1.2 mg/kg rocuronium)
Options:
A) 4 mg/kg
B) 16 mg/kg
C) 2 mg/kg
Shallow/Medium Blockade - C) 2 mg/kg
Deep Blockade - A) 4 mg/kg
Immediate Reversal - B) 16 mg/kg
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Under which of the following conditions is no dose adjustment needed when administering sugammadex? (Select all that apply)
A) Patient is older than 65 years
B) Patient is obese
C) Patient is under 18 years
D) Based on patient’s gender
A) Patient is older than 65 years
B) Patient is obese
D) Based on patient’s gender
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What is one notable characteristic of sugammadex?
A) Inexpensive
B) Very expensive
C) Free of side effects
D) Causes sedation
B) Very expensive
Can be used as a rescue drug if Roc is given in and can’t intubate, can’t ventilate situation.
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