Benzodiazepines Flashcards
Which of the following medications are classified as benzodiazepines? (Select all that apply)
A) Midazolam (Versed)
B) Diazepam (Valium)
C) Lorazepam (Ativan)
D) Flumazenil (Romazicon)
E) Morphine
A) Midazolam (Versed)
B) Diazepam (Valium)
C) Lorazepam (Ativan)
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Which of the following are principal pharmacologic effects of benzodiazepines? (Select 5 that apply)
A) Sedation
B) Analgesia
C) Anxiolysis
D) Hypnotic
E) Anticonvulsant
F) Spinal cord-mediated skeletal muscle relaxation
G) Anti-inflammatory
A) Sedation
C) Anxiolysis
D) Hypnotic
E) Anticonvulsant
F) Spinal cord-mediated skeletal muscle relaxation
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Which of the following correctly ranks the potency of these benzodiazepines from most potent to least potent?
A) Diazepam > Midazolam > Lorazepam
B) Lorazepam > Midazolam > Diazepam
C) Midazolam > Lorazepam > Diazepam
D) Midazolam > Diazepam > Lorazepam
B) Lorazepam > Midazolam > Diazepam
Memory Trick: “LMD – Like Most Drugs”
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___ is approximately 5 times more potent than Midazolam.
A) Diazepam
B) Lorazepam
C) Flumazenil
D) Alprazolam
B) Lorazepam
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___ is approximately 5 times more potent than Diazepam.
A) Lorazepam
B) Midazolam
C) Alprazolam
D) Flumazenil
B) Midazolam
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What are the typical cardiovascular effects of benzodiazepines when given at a sedative dose?
A) Significant increase in blood pressure and heart rate
B) Minimal effects with a small, possible drop in blood pressure
C) Severe hypotension and bradycardia
D) Complete suppression of the cardiovascular system
B) Minimal effects with a small, possible drop in blood pressure
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Which of the following statements best describes the respiratory effects of benzodiazepines?
A) Benzodiazepines always cause severe respiratory depression regardless of dose.
B) Benzodiazepines cause respiratory depression that is dose-dependent.
C) Benzodiazepines have no effect on respiratory function.
D) Benzodiazepines only affect respiratory function when combined with other drugs.
B) Benzodiazepines cause respiratory depression that is dose-dependent.
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At higher doses, benzodiazepines can depress which of the following functions?
A) Blood pressure regulation
B) Airway reflexes and ability to swallow
C) Immune response
D) Kidney function
B) Airway reflexes and ability to swallow
Patient must be monitored following administration of BZDs, especially respiratory function.
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Normally, breathing is driven by levels of ___ in the blood, but in some patients, ___ levels trigger breathing.
A) CO₂; Oxygen
B) Oxygen; CO₂
C) CO₂; Nitrogen
D) Nitrogen; Oxygen
A) CO₂; Oxygen
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What effect do benzodiazepines have on certain patients for respiration?
A) They increase the drive to breathe.
B) They depress the hypoxic drive to breathe.
C) They have no effect on respiratory drive.
D) They stimulate the hypoxic drive to breathe.
B) They depress the hypoxic drive to breathe.
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Which of the following patient populations are at risk for having a depressed hypoxic drive to breathe when using benzodiazepines? (Select 3 that apply)
A) Patients with chronic COPD
B) Patients with sleep apnea
C) Patients with morbid obesity
D) Patients with hypertension
A) Patients with chronic COPD
B) Patients with sleep apnea
C) Patients with morbid obesity
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Any dose, in any patient, can cause apnea when using ______.
A) Lorazepam
B) Midazolam
C) Diazepam
D) Flumazenil
B) Midazolam
Do not administer Midazolam and then walk away!
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Benzodiazepines are ________ with opioids, meaning they can enhance each other’s effects, particularly increasing the risk of respiratory depression.
A) antagonistic
B) synergistic
C) neutral
D) incompatible
B) synergistic
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Benzodiazepines ________ blunt the sympathetic nervous system (SNS) response to intubation.
A) completely
B) partially
C) do not
D) strongly
C) do not
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_______ and _______ have almost no respiratory depression when used alone.
A) PO Diazepam and Lorazepam
B) IV Midazolam and Lorazepam
C) PO Alprazolam and Clonazepam
D) IV Diazepam and Midazolam
A) PO Diazepam and Lorazepam
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