Narcotics: Morphine Flashcards
Morphine is classified as an __________, meaning it binds to and activates opioid receptors.
A) Antagonist
B) Agonist
C) Antihistamine
D) Enzyme
B) Agonist
Throw back to Dr. T
21
What is the typical IV dose range for Morphine when used for post-operative pain management?
A) 1-5 mg
B) 5-20 mg
C) 20-30 mg
D) 10-40 mg
B) 5-20 mg titrated
21
After intrathecal administration, Morphine can cause delayed respiratory depression lasting up to __________ hours.
A) 6
B) 12
C) 18
D) 24
D) 24
21
Morphine has dose-dependent release of which chemical that may lead to side effects?
A) Epinephrine
B) Dopamine
C) Histamine
D) Serotonin
C) Histamine
21
With high doses, Morphine can lead to a decrease in __________.
A) PVR
B) Heart rate
C) Respiratory rate
D) Blood pressure
B) Peripheral vascular resistance (PVR)
21
In patients with liver failure, renal failure, or advanced age, Morphine’s half-life is:
A) Shortened
B) Unaffected
C) Prolonged
D) Doubled
C) Prolonged
21
True or False
Morphine has 2 active metaboiltes
True
Morphine-6-glucuronide (M6G)
More potent than morphine and is responsible for the analgesic effect of morphine
Morphine-3-glucuronide (M3G)
An inactive metabolite that may produce excitatory effects and is responsible for some side effects of high-dose morphine
21
Morphine Intra op dose is
A. 1-10
B. 5-20
C.8-20
D.3-5
A.1-10
Onset for Morphine is
A. 5-15min
B. 8-12 min
C. 10-20min
D. 1-4 mine
C. 10-20min
duration of Morphine is
A.4-8hours
B.8-24hours
C.1-3hours
D. 4-5 hours
D. 4-5hours