Induction Agent: Methohexital (Brevital)

Question 1

Methohexital is commonly known by which brand name?
A) Propofol
B) Versed
C) Brevital
D) Diprivan

Answer 1

C) Brevital

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Question 2

Methohexital (Brevital) is often used as an induction agent in anesthesia and is supplied in which of the following concentrations?

A) 0.5% and 1% solutions
B) 1% and 2% solutions
C) 2% and 3% solutions
D) 5% and 10% solutions

Answer 2

B) 1% and 2% solutions

1% (10 mg/cc) or 2% (20 mg/cc) solution.

Usually a 50cc vial of 1% solution.

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Question 3

Which of the following effects may Methohexital cause even at low doses?

A) Sedation and hypotension
B) Bradycardia and hiccoughs
C) Bradycardia and hypotension
D) Myoclonus and hiccoughs

Answer 3

D) Myoclonus and hiccoughs

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Question 4

The typical adult dose for Methohexital (Brevital) is __________ mg/kg.

A) 0.5
B) 1
C) 1.5
D) 2

Answer 4

C) 1.5mg/kg

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Question 5

The distribution time of Methohexital (Brevital) is approximately:
A) 2.6 minutes
B) 4.4 minutes
C) 5.6 minutes
D) 7.2 minutes

Answer 5

C) 5.6 minutes

Question 6

The clearance rate of Methohexital is approximately:

A) 11 ml/kg/min
B) 13 ml/kg/min
C) 15 ml/kg/min
D) 18 ml/kg/min

Answer 6

A) 11 ml/kg/min

Question 7

The elimination half-life of Methohexital is approximately __________ hours, which affects its duration of action.

A) 1
B) 2
C) 4
D) 6

Answer 7

C) 4hour

Question 8

At high doses, Methohexital is used to __________ seizures, even though it can induce seizures at ________ doses.

A) Prevent, high
B) Treat, low
C) Provoke, high
D) Enhance, low

Answer 8

B) Treat, low

cause seizure activity at low doses = epileptogenic

Question 9

Which of the following is a potential side effect of Methohexital that may require monitoring during anesthesia?

A) Drowsiness
B) Airway irritability
C) Constipation
D) Itching

Answer 9

B) Airway irritability

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Question 10

Methohexital is commonly used in Electroconvulsive Therapy (ECT) because it:

A) Has a long duration of action
B) Depresses seizure activity
C) Does not depress seizure activity
D) Causes significant muscle relaxation

Answer 10

C) Does not depress seizure activity

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Question 11

Which of the following procedures is Methohexital especially suitable for?

A) Painful, lengthy surgeries
B) Rapid, non-painful procedures
C) Rapid muscle relaxation
D) Procedures with high blood loss

Answer 11

B) Rapid, non-painful procedures

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Question 12

One common use of Methohexital is for __________, as it allows for rapid induction and minimal interference with seizure monitoring.

A) Pain management
B) Seizure focus mapping
C) Deep sedation
D) Treating hypotension

Answer 12

B) Seizure focus mapping

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Question 13

In addition to ECT, Methohexital may also be used for __________.

A) Cardioversion
B) Angioplasty
C) Aneurysm repair
D) Endoscopy

Answer 13

A) Cardioversion

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