Glycopyrrolate / Robinul

Question 1

What is the onset time for Glycopyrrolate (Robinul®)?

A) 1-2 minutes
B) 2-3 minutes
C) 5 minutes
D) 10 minutes

Answer 1

B) 2-3 minutes

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Question 2

What is the duration of action for Glycopyrrolate (Robinul®)?

A) 30 minutes
B) 1 hour
C) 2 hours
D) 4 hours

Answer 2

C) 2 hours

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Question 3

What is the concentration of Glycopyrrolate (Robinul®) when supplied?

A) 0.1 mg/cc
B) 0.2 mg/cc
C) 1 mg/cc
D) 2 mg/cc

Answer 3

B) 0.2 mg/cc

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Question 4

Which of the following is true about the quaternary structure of Glycopyrrolate? (Select 2 that apply)

A) It does not cross the blood-brain barrier (BBB).
B) It provides significant sedation.
C) It has no sedative effect.
D) It enhances blood-brain barrier permeability.

Answer 4

A) It does not cross the blood-brain barrier (BBB).

C) It has no sedative effect.

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Question 5

Which of the following effects are associated with Glycopyrrolate? (Select all that apply-3)

A) Tachycardia (++).
B) Bronchodilation (++).
C) Sedation (++).
D) Antisialagogue (+++).
E) Greater tachycardia effect than Atropine.

Answer 5

A) Tachycardia (++).
B) Bronchodilation (++).
D) Antisialagogue (+++).

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Question 6

Glycopyrrolate is commonly used with which medication to counteract bradycardia effects?

A) Atropine
B) Edrophonium
C) Neostigmine
D) Physostigmine

Answer 6

C) Neostigmine

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