Succynilcholine Flashcards
Succinylcholine
Mechanism
Cholinergic r agonist=> competes with ach neuromuscular junctions:when bound causes initial wave of widespread neuromuscular depolarization ach binding and stimulation
Anectine
Class
Depolarizing neuromuscular blocker
Anectine
Pharmo
O: 30-60 sec IV 2-3 min I’m
P: 1-3 min
D:2-3 min IV, 10-30 I’m
H: 5-10 min
Succinylcholine
Indications
Temp. Paralysis to facilitate eti and muscle tone or seizures prevent it
Anectine
Contraindications
Penetrating eye injuries, narrow angled glaucoma nown or suspected hyperkalemia, HX of malignant hyperthermia
Succinylcholine
SE
Wheezing, apnea, ICP, HTN, respiratory depression
Anectine
Dose
1-2 mg/kg IV io
pedi 1 mg/ kg
Succinylcholine
Precautions
May cause fractures in children due to muscle fasiculations,
- dysrhythmias and cardiac arrest
Anectine
D2d
Potentiate by lidocaine, b blocker, procainamide, mag, and other neuromuscular blockers