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Individual Drugs > Magnesium Sulfate > Flashcards

Magnesium Sulfate Flashcards

1
Q

Generic/Trade Name

MAGNESIUM SULFATE

A

MAGNESIUM SULFATE

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2
Q

MAGNESIUM SULFATE

Drug Classification:

A

Electrolyte / Antidysrhythmic / Mineral

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3
Q

MAGNESIUM SULFATE

Mechanism of Action:

A

Physiologic Ca2+ channel blocker ⇒ blocks neuromuscular transmission, causes CNS depression and smooth muscle relaxation

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4
Q

MAGNESIUM SULFATE

Onset of Action

A
  • Immediate IV
  • 1 hour IM
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5
Q

MAGNESIUM SULFATE

Peak Effects

A

Varies

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6
Q

MAGNESIUM SULFATE

Duration of Effect

A

1 hour

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7
Q

MAGNESIUM SULFATE

Half-Life

A

N/A

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8
Q

MAGNESIUM SULFATE

Indications/Field Use:

A
  • Severe Asthma / Bronchospasm
  • Severe refractory VF or pulseless VT w/ hypoMg2+, and Torsades de Pointes
  • Post-MI prophylaxis of dysrhythmias
  • Eclampsia, Pre-Term Labor
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9
Q

MAGNESIUM SULFATE

Contraindications:

A
  • Pt. w/ 3° heart block
  • shock
  • severe/persistent hypertension
  • impaired renal function
  • hypocalcemia
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10
Q

MAGNESIUM SULFATE

Side Effects/Adverse Reactions:

A
  • Flushing
  • sweating
  • bradycardia
  • decreased deep tendon reflexes
  • drowsiness
  • respiratory depression
  • dysrhythmias
  • hypotension
  • hypothermia
  • itching
  • rash
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11
Q

MAGNESIUM SULFATE

ADULT Asthma Dose:

A

2g in 100cc NS IV, IO infusion over 10 minutes

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12
Q

IPRATROPIUM BROMIDE (Atrovent®)

ADULT Dose: VT,VF, Torsades-no pulse:

VT/Torsades +pulse :

A
  • 2g IVP (IO) over 1-2 minutes
  • 1-2g in 50-100cc NS, slow IVP (IO) over 5-60 minutes
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13
Q

MAGNESIUM SULFATE

ADULT Dose: Eclampsia

A
  • 2-4g slow IV, IO over 25 min
  • IM if IV access unavailable
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14
Q

MAGNESIUM SULFATE

PEDI Asthma Dose:

A
  • 25-50mg/kg slow IV, IO infusion over 15-30min
  • max dose 2g
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15
Q

MAGNESIUM SULFATE

PEDI Dose: VT-no pulse:

VT+pulse (PEDI):

A
  • 25-50mg/kg IVP (IO),
  • max dose 2g
  • 25-50mg/kg IV, IO over 10-20 minutes,
  • max dose 2g
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16
Q

MAGNESIUM SULFATE

Precautions:

A
  • Monitor vitals
  • watch for respiratory depression
  • have CaCl2 available if OD
17
Q

MAGNESIUM SULFATE

Drug-Drug Interactions:

A

Cardiac conduction abnormalities if given with digitalis

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