Racemic Epinephrine Flashcards
0
Q
Racemic epinephrine(vaponiphrine) Mechanism
A
A and b agonist(slightly b selective) => bronchodilator, decreased mucous membrane secretions, relieves subglottic edema
1
Q
Racemic epinephrine(vaponiphrine) Class
A
Sympathomimetic
2
Q
Racemic epinephrine(vaponiphrine) Pharmacokinetics
A
Onset: < 5 min inhaled
Peak: 5-15 min
Duration: 1-3 hrs
1/2 life: n/a
3
Q
Racemic epinephrine(vaponiphrine) Indications
A
- croup (laryngotracheobronchitis)
4
Q
Racemic epinephrine(vaponiphrine) Contraindications
A
- hypertension
- epiglottitis
- tachydysrhythmias
5
Q
Racemic epinephrine(vaponiphrine) Side effects
A
- restlessness
- headache
- anxiety
- dizziness
- hypertension
- tachycardia
- paradoxical bronchspasm
- nv
6
Q
Racemic epinephrine(vaponiphrine) Dose
A
Pedi: 5.0 mg 1:1000 epi in 2.5-3.0 ml NS, nebulized with oxygen
Or: 0.25-0.75 of 2.25% solution in 2ml NS nebulized with oxygen
7
Q
Racemic epinephrine(vaponiphrine) Precautions
A
- rebound or worse effects when med wears off
8
Q
Racemic epinephrine(vaponiphrine) Drug to drug
A
- additive effects with other sympathomimetics
