Ipatropium Bromide (Atrovent) Flashcards
Generic/Trade Name
IPRATROPIUM BROMIDE
Atrovent®
Generic/Trade Name
Atrovent®
IPRATROPIUM BROMIDE
(Atrovent®)
Drug Classification:
Anticholinergic / Parasympatholytic
IPRATROPIUM BROMIDE (Atrovent®)
Mechanism of Action:
Muscarinic ACh-R blocker⇒ inhibits parasympathetic stimulation and vagally mediated responses by preventing increase in intracellular cGMP in bronchial smooth muscle⇒ dries respiratory tract secretions and allows for bronchodilation
IPRATROPIUM BROMIDE (Atrovent®)
Onset of Action
Varies
(Atrovent®)
Peak Effects
1.5-2.0 hours
IPRATROPIUM BROMIDE (Atrovent®)
Duration of Effect
4-6 hours
IPRATROPIUM BROMIDE (Atrovent®)
Half-Life
1.5-2.0 hours
(Atrovent®)
Indications/Field Use:
- Bronchial Asthma
- Reversible bronchospasm associated with COPD
IPRATROPIUM BROMIDE (Atrovent®)
Contraindications:
- Patients with history of hypersensitivity to this drug;
- should not be used as primary acute treatment of bronchospasm
IPRATROPIUM BROMIDE (Atrovent®)
Side Effects/Adverse Reactions:
- Anxiety
- HA
- palpitations
- dizziness
- nervousness
- rash
- N+V
(Atrovent®)
ADULT Dose:
- Small-volume nebulizer: 50mcg –typically administered with a ß agonist
- MDI
IPRATROPIUM BROMIDE (Atrovent®)
PEDI Dose:
- Small-volume nebulizer: (PEDI) 250-500mcg q20min PRN
- MDI
IPRATROPIUM BROMIDE (Atrovent®)
Precautions:
- BP, pulse, and EKG should be monitored,
- use caution w/ patients w/ known heart disease or HTN and elderly,
- auscultate LS before and after treatment
IPRATROPIUM BROMIDE (Atrovent®)
Drug-Drug Interactions:
Few prehospitally, not specified
