Subarachnoid Block Flashcards

1
Q

How many pairs of spinal nerves are there and how

are they grouped anatomically?

A

There are 31 pairs of spinal nerves: 8 cervical, 12 thoracic, 5
lumbar, 5 sacral, and 1 coccygeal.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 9.

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2
Q

What is the only absolute contraindications to spinal

anesthesia?

A

Patient refusal
Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC,
Ortega R. Clinical Anesthesia. 7th ed. Philadelphia, PA:
Lippincott Williams and Wilkins; 2013: 929.

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3
Q

From exterior to interior, name the structures the
spinal needle passes through when performing a
subarachnoid block via the midline approach.

A

Skin, subcutaneous tissue, supraspinous ligament, interspinous
ligament, ligamentum flavum, dura mater, arachnoid mater, and
subarachnoid space.
Longnecker DE, Newman MF, Brown DL, Zapol WM.
Anesthesiology. 2nd ed. New York: McGraw-Hill; 2012: 791.

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4
Q

From exterior to interior, what structures will the
needle traverse when performing a subarachnoid
block using a paramedian approach?

A

Skin, subcutaneous tissue, paraspinous muscle, ligamentum
flavum, dura mater, arachnoid mater, and subarachnoid space.
Longnecker DE, Newman MF, Brown DL, Zapol WM.
Anesthesiology. 2nd ed. New York: McGraw-Hill; 2012: 792.

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5
Q

Where is cerebrospinal fluid created and absorbed?

A

CSF is created in the choroid plexus and absorbed in the
arachnoid granulations (remember C for Create and Choroid
and A for Absorb and Arachnoid)
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081

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6
Q

What are some of the relative contraindications to

spinal anesthetic?

A

Hypovolemia, sepsis, increased intracranial pressure,
coagulopathy or thrombocytopenia, and infection at the
puncture site. Other major contraindications include:
conditions resulting in left ventricular outflow obstruction such
as aortic stenosis or hypertrophic subaortic stenosis restrict the
ability of the heart to increase cardiac output as compensation
for hypotension due to the sympathectomy induced by neuraxial
anesthesia.
Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC,
Ortega R. Clinical Anesthesia. 7th ed. Philadelphia, PA:
Lippincott Williams and Wilkins; 2013: 929.

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7
Q

What are the major potential complications arising

from a spinal anesthetic?

A

Neurologic dysfunction, allergic reaction, anterior spinal artery
syndrome, trauma, drug toxicity, infection, hematoma, and total
spinal blockade.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 166.

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8
Q

How far does the subarachnoid space extend

caudally in adults?

A

The subarachnoid space extends from the foramen magnum to
S2 in adults.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 943

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9
Q

How far does the subarachnoid space extend

caudally in children?

A

The subarachnoid space extends from the foramen magnum to
S3 in children.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 943.

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10
Q

How far does the spinal cord extend caudally in

children?

A

The spinal cord extends to L3 in children.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 943.

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11
Q

How far does the spinal cord extend caudally in

adults?

A

The spinal cord extends to L2 in adults.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1071.

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12
Q

Where are the most dependent portions of the spinal

column in the supine position?

A

Normally, in the supine position, the most dependent portion of
the spinal column occurs at T4-T8 with the peak of the
thoracolumbar curvature occurring at T4. This is important in
relation to hyperbaric spinal solutions which will tend to pool in
the T4-T8 curvature but limit their ascent above T4 in the supine
position.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 956-957.

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13
Q

Where are the two enlargements in the spinal cord

and what causes them?

A

The cervical enlargement occurs at C4-T1 and the lumbar
enlargement which occurs from L2-S3. The cervical
enlargement is due to the nerve roots that produce the brachial
plexus and the lumbar enlargement produces the lumbar plexus.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1072.

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14
Q

What external anatomic landmark can be used to

identify the L4 interspace?

A

The superior aspect of the iliac crest can be palpated at the
level of the L4 interspace.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 1.

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15
Q

What spinal landmark corresponds with the level of

the posterior superior iliac spine?

A

S2
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 1.

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16
Q

What spinal landmark corresponds with the level of

the posterior superior iliac spine?

A

S2
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 1.

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17
Q

In what positions can a subarachnoid block be

performed?

A

A subarachnoid block can be performed in the sitting, lateral, or
prone positions.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1079.

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18
Q

For what procedures is the sitting position for

subarachnoid block advantageous?

A

The sitting position is advantageous for vaginal or urologic
procedures where a ‘saddle’ block is preferable.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1079.

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19
Q

For what procedures would it be advantageous to

perform a subarachnoid block in the prone position?

A

The prone position is advantageous for rectal procedures
because the patient can be placed into position for the surgery
before the block is performed.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1079.

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20
Q

For what procedures is it advantageous to perform a

subarachnoid block in the lateral position?

A

The lateral position is advantageous for surgeries where you
would prefer that the drug be concentrated on one side more
than the other, such as hip surgery.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1079.

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21
Q

How should the patient be instructed to change their
posture to make performing a spinal anesthetic
easier?

A

They should be encouraged to arch their back in the shape of a
C which opens up the intervertebral spaces and makes
insertion of the needle easier.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1079.

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22
Q

Is it appropriate to wipe off excess Betadine with an
alcohol prep prior to inserting the spinal needle for a
subarachnoid block? Why or why not?

A

No, you should use a dry sterile gauze to wipe away excess
Betadine after prepping the skin. Alcohol neutralizes the iodine
solution and reduces its ability to function as an antiseptic.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1080.

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23
Q

If Betadine is used as the antiseptic to clean the skin
prior to performing a spinal anesthetic, how long
should you wait after applying the Betadine before
beginning the procedure and why?

A

You should wait at least 1 minute before beginning the spinal so
that the Betadine has ample opportunity to dry. Then, you
should wipe away any remaining liquid Betadine off of the skin.
If Betadine (or any povidone-iodine solution) is introduced into
the subarachnoid space, it can produce a chemical
arachnoiditis.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1080.

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24
Q

You are inserting a spinal needle during a
subarachnoid block and feel a ‘pop’. What might this
indicate and what should you do next?

A

The ‘pop’ could represent the loss of resistance sensation felt
as the needle penetrates beyond the ligamentum flavum and
through dura and enters the subarachnoid space. You should
withdraw the stylet and see if CSF flow is present.
Longnecker DE, Newman MF, Brown DL, Zapol WM.
Anesthesiology. 2nd ed. New York: McGraw-Hill; 2012: 791.

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25
Q

During a subarachnoid block, you inserted the
needle, felt a ‘pop’, removed the stylet and see CSF
flow, what is the recommended step to take next?

A

It is recommended to rotate the needle 360 degrees in 90
degree increments to make sure that flow is constant in all four
quadrants to ensure proper needle placement. Once you have
verified the needle position, you can verify CSF flow by
aspirating with the spinal syringe and begin administering the
medication for the spinal anesthetic.
Longnecker DE, Newman MF, Brown DL, Zapol WM.
Anesthesiology. 2nd ed. New York: McGraw-Hill; 2012: 791-
792.

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26
Q

How is a paramedian approach to a subarachnoid

block performed?

A

A skin wheal is raised 1 cm lateral to the superior tip of the
spinous process at the lumbar level you wish to access. The
tissue below the skin wheal is infiltrated with local anesthetic.
The introducer and needle are then inserted at a 10-15 degree
angle toward midline.
Longnecker DE, Newman MF, Brown DL, Zapol WM.
Anesthesiology. 2nd ed. New York: McGraw-Hill; 2012: 791-
792

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27
Q

When performing spinal anesthesia, two ‘pops’ are
often felt. The first pop encountered is due to the
needle penetrating what structure?

A

The first ‘pop’ is the needle penetrating the ligamentum flavum
and the second is the needle penetrating the dura mater.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 955.

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28
Q

While inserting the spinal needle during a
subarachnoid block, you feel as if you have struck
bone. What should you do next?

A

Carefully check to see if the needle is midline. If the needle is
directed away from midline, withdraw it and reposition the
needle. If it appears to be in the midline, then ‘walk’ the needle
caudally until the subarachnoid space is encountered.
Longnecker DE, Newman MF, Brown DL, Zapol WM.
Anesthesiology. 2nd ed. New York: McGraw-Hill; 2012: 791.

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29
Q

What are the most important factors that determine
the spread of local anesthetics within the
cerebrospinal fluid during a subarachnoid block?

A

The total dose of anesthetic, the site of injection, the baricity of
the local anesthetic, and the position of the patient during and
immediately after injection.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

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30
Q

What two factors determine the duration of action of

a spinal anesthetic?

A

The anesthetic drug used and the total dose given.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

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31
Q

How does the volume of the local anesthetic injected
affect the duration and spinal level achieved with the
block?

A

Volumes between the ranges of 1 mL and 14 mL has been
thoroughly tested and has little effect on the duration of action
of the spinal anesthetic or the sensory level achieved.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1082.

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32
Q

How does the volume of the local anesthetic injected
affect the duration and spinal level achieved with the
block?

A

Volumes between the ranges of 1 mL and 14 mL has been
thoroughly tested and has little effect on the duration of action
of the spinal anesthetic or the sensory level achieved.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1082.

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33
Q

How does the addition of a vasoconstrictor to a local
anesthetic affect the duration of action of a spinal
anesthetic?

A

The addition of a vasoconstrictor to the local anesthetic used in
a subarachnoid block will prolong the duration of action of the
block.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

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34
Q

What is the normal specific gravity of CSF?

A

1.004 to 1.009
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

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35
Q

What is the difference between specific gravity and

baricity?

A

Specific gravity is the comparison between the density of a
solution (such as CSF) when compared to water, which is
assigned a value of 1. A solution that has a higher density than
water has a value higher than 1. A solution with a density lower
than water has a specific gravity less than 1. Baricity is the
relationship of one solution’s density to the density of another
solution. For example if one solution is more dense than
another, it is said to be hyperbaric in relation to that solution. If
the solution in question is less dense to another solution, it is
said to be hypobaric. If the two solutions have the same
density, they are said to be isobaric with respect to one another.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081

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36
Q

How will hypobaric solutions move when injected into

the subarachnoid space?

A

Hypobaric solutions are less dense (lighter) than CSF and will
‘float’ to the highest possible anatomic position within the
subarachnoid space.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

37
Q

How will hyperbaric solutions move when injected

into the subarachnoid space?

A

Hyperbaric solutions are more dense (heavier) than CSF and
will ‘sink’ to the lowest possible position in the subarachnoid
space.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

38
Q

How will isobaric solutions move when injected into

the subarachnoid space?

A

Isobaric solutions have a density that is equal to CSF and will
generally remain in the position they are injected.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081

39
Q

What is the traditional technique to make a spinal

anesthetic hypobaric?

A

Dissolving the drug in sterile water will result in a solution that is
hypobaric in relationship to the CSF.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

40
Q

What is the traditional technique for making a spinal

anesthetic hyperbaric?

A

Dissolving the drug in 5% or 8% dextrose will make the solution
hyperbaric.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

41
Q

What is the traditional technique for making a

solution isobaric?

A

Dissolving the solution in cerebrospinal fluid will result in an
isobaric solution.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

42
Q

If a hyperbaric spinal anesthetic is injected below the
level of L3 and the patient is left in the sitting
position, how will the local anesthetic migrate in the
subarachnoid space?

A

The local anesthetic will drift inferiorly and result in a ‘saddle
block’.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1082.

43
Q

Theoretically, if a hyperbaric spinal anesthetic is
injected at the L3 interspace and then the patient is
positioned supine, how will the drug spread through
the subarachnoid space and why?

A

Because the lumbar spinal curve peaks anteriorly at about L3,
placing the patient supine would result in the spread of the drug
in both a cephalad and caudal direction.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1082.

44
Q

What is the mechanism of action by which the
addition of epinephrine to a spinal anesthetic
prolongs its duration?

A

It is thought that the duration of action is prolonged by
vasoconstriction and resultant decrease in the diffusion of the
drug away from the site of action, by a direct nociceptive effect,
or by a combination of these two actions.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081

45
Q

What is the total volume of cerebrospinal fluid at any

given time in a normal adult?

A

About 150 mL.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 579.

46
Q

What is the normal CSF pressure?

A

CSF pressure is normally maintained between 10 and 20 cm
H2O.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

47
Q

About how much CSF is contained within the

subarachnoid space?

A

Between 30 and 80 mL.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

48
Q

How does the specific gravity of the cerebrospinal

fluid change with age? Why does it change?

A

The specific gravity of the CSF tends to increase as the patient
ages, primarily due to increases in glucose and protein content.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

49
Q

What patient conditions may increase the specific
gravity of the CSF? What patient conditions may
decrease the specific gravity of the CSF?

A

The specific gravity of the CSF can increase with hyperglycemia
and uremia and may decrease with liver disease.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

50
Q

What patient conditions may increase the specific
gravity of the CSF? What patient conditions may
decrease the specific gravity of the CSF?

A

The specific gravity of the CSF can increase with hyperglycemia
and uremia and may decrease with liver disease.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

51
Q

About how much cerebrospinal fluid is produced

each hour?

A

About 30 mL per hour
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 690.

52
Q

About how much cerebrospinal fluid is produced

each day?

A

500 mL
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

53
Q

What factors are associated with an increased height

of spinal block?

A

Conditions that result in increased abdominal pressure or
engorgement of epidural veins such as pregnancy, ascites,
abdominal tumors, kyphoscoliosis, or increased age reduce the
CSF volume and increase the height of spinal blockade. In
pregnant patients, the dose of spinal anesthetic to reach
acceptable levels is one-third that of non-pregnant patients.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 956.

54
Q

How does the addition of sodium bicarbonate affect

a spinal anesthetic?

A

Sodium bicarbonate 0.2 mL of a 0.42% solution is thought to
shorten the onset of a spinal anesthetic, but does not prolong
the duration of block.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 133.

55
Q

What doses of epinephrine, clonidine, or
phenylephrine would be appropriate to mix with a
spinal anesthetic to prolong the duration of the block?

A

Epinephrine 0.2 to 0.3 mg, clonidine 75 to 100 mcg, or
phenylephrine 2 to 5 mg can be added to a spinal anesthetic to
prolong the duration without resulting in any significant
cardiovascular changes.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081-1082.

56
Q

How does the Taylor approach differ from the

paramedian approach?

A

The Taylor approach is a lateral approach, but utilizes the L5-
S1 interspace which is typically the largest interspace. The
posterior superior iliac spine is identified and skin wheal is
raised 1 cm medial and caudad to the inferior border of the
posterior superior iliac spine. After local infiltration, the needle
is directed 45 degrees medial toward the L5-S1 interspace.
Longnecker DE, Newman MF, Brown DL, Zapol WM.
Anesthesiology. 2nd ed. New York: McGraw-Hill; 2012: 792.

57
Q

If you encounter bone during a subarachnoid block
via the paramedian approach, how should you
proceed?

A

You should walk the needle more cephalad and then medial
until the subarachnoid space is encountered.
Longnecker DE, Newman MF, Brown DL, Zapol WM.
Anesthesiology. 2nd ed. New York: McGraw-Hill; 2012: 792.

58
Q

If you encounter bone during a paramedian
approach to a subarachnoid block, what specific
bone have you most likely encountered?

A

The most common bone to encounter when performing a
subarachnoid block via a paramedian approach is the caudad
lamina.
Longnecker DE, Newman MF, Brown DL, Zapol WM.
Anesthesiology. 2nd ed. New York: McGraw-Hill; 2012: 792

59
Q

How does a spinal anesthetic affect vital capacity?

Tidal volume?

A

Vital capacity can diminish due to decreased intercostal muscle
activity. The tidal volume is left unchanged.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 946.

60
Q

Why is urinary retention commonly associated with a
subarachnoid block? Is urinary incontinence a
complication of subarachnoid block?

A

The blockade of the autonomic fibers to the bladder from the S2-
S4 nerve roots results in a decreased ability to void, so urinary
retention is a common complication but urinary incontinence is
not.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 947.

61
Q

How does a spinal anesthetic affect adrenal function?

A

Sympathectomy to the adrenal glands results in a decreased
stress response to surgical stimulation which, by limiting the
release of stress hormones, also limits any resulting increase in
blood sugar.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 947.

62
Q

How does a spinal anesthetic affect the

gastrointestinal system?

A

The sympathectomy produced by spinal anesthesia results in
unopposed vagal activity. This increased parasympathetic
activity results in increased peristalsis and a contracted gut.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 946-947.

63
Q

At what spinal levels would you expect a patient to

complain of dyspnea?

A

A sensory level of T2-T4 can cause loss of sensory perception
of abdominal wall and intercostal muscle movement resulting in
a sensation of dyspnea despite normal respiration. A level of
C2-C3 can result in phrenic nerve and intercostal muscle
paralysis resulting in hypoxia, hypercarbia, or respiratory arrest.
Longnecker DE, Newman MF, Brown DL, Zapol WM.
Anesthesiology. 2nd ed. New York: McGraw-Hill; 2012: 800.

64
Q

A patient with a T6 sensory level exhibits
bradycardia and hypotension. What is the most
likely cause?

A

In addition to the hypotension attributed to the increase in
venous capacitance, blockade of the cardioacceleratory fibers
at the T1 to T4 level can result in bradycardia and decreased
myocardial contractility. Since a sympathetic blockade is
typically 2 segments above a sensory block, a sensory block at
T6 or higher could result in blockade of the cardioacceleratory
fibers.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 945-946.

65
Q

What are the causes of most allergic reactions to

spinal anesthetics?

A

Most allergies are actually due to anxiety, epinephrine
response, vasovagal reactions, or systemic toxic reactions to
local anesthetics. The actual incidence of an anaphylactic
reaction to a spinal anesthetic is 1 in 13,000.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 170.

66
Q

What are the causes of most allergic reactions to

spinal anesthetics?

A

Most allergies are actually due to anxiety, epinephrine
response, vasovagal reactions, or systemic toxic reactions to
local anesthetics. The actual incidence of an anaphylactic
reaction to a spinal anesthetic is 1 in 13,000.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 170.

67
Q

If a patient has a true allergic reaction to a spinal
anesthetic, what are the most common presenting
symptoms?

A

It is typically limited to a hypersensitivity reaction that results in
erythema and/or edema of the mucous membranes.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 170.

68
Q

What local anesthetics are most predisposed to

causing an allergic reaction and why?

A

The ester local anesthetics such as procaine, chloroprocaine,
tetracaine, and benzocaine are most commonly implicated in
IgE-mediated allergic reactions. The higher risk is due to the
para-aminobenzoic acid preservative to which patients have
had previous exposure. PABA is found in common items such
as lotions, sunscreens, cosmetics, sulfonamides, and some
foods.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 170.

69
Q

What is the incidence and cause of cardiac arrest

during spinal anesthesia?

A

The incidence of cardiac arrest in spinal anesthesia is about 1
in 4,000. The cause is blockade of the cardioacceleratory fibers
from T1 to T5 and a drop in venous return. It is usually
preceded by bradycardia and hypotension.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 171.

70
Q

What is transient neurologic syndrome?

A

TNS, which has historically been referred to as transient
radicular irritation, is defined as pain in the lower back or
buttocks that may radiate to one or both legs after a spinal
anesthetic.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 172.

71
Q

How long does transient neurologic syndrome

typically last?

A

About 1 week.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 172.

72
Q

What local anesthetics are associated with the

highest incidence of transient neurologic syndrome?

A

Mepivicaine and lidocaine have the highest association with
TNS and bupivacaine has the lowest incidence.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 173.

73
Q

What is cauda equina syndrome?

A

Cauda equina syndrome consists of lower back pain, sciatica,
motor and sensory loss, and bladder and bowel dysfunction that
typically occurs due to trauma, lumbar disc disease, ankylosing
spondylitis, tumors, or abscesses in the lumbar area. It has
also been associated with prolonged exposure of the cauda
equina to high doses or high concentrations of local anesthetics
that cause direct neurotoxicity.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 173.

74
Q

What is arachnoiditis and what causes it?

A

Arachnoiditis in an inflammatory disorder of the arachnoid mater
which surrounds the spinal cord and cauda equina. It can be
caused by exposure of the arachnoid membrane to povidoneiodine
solution, vasoconstrictors, local anesthetics, blood, and
contrast media.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 173.

75
Q

Why is the cauda equina susceptible to injury?

A

The cauda equina is composed of nerve roots below the
terminal level of the spinal cord. Because these nerves have an
underdeveloped epineurium and are hypovascular relative to
the rest of the cord, they are more susceptible to injury.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 173.

76
Q

What are the symptoms of arachnoiditis?

A

Lower back and leg pain that increases with activity that may
include a wide range of sensory and motor alterations. It
usually is not progressive, but significant improvement is not
likely.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 173.

77
Q

What is anterior spinal artery syndrome?

A

Anterior spinal artery syndrome is characterized by painless
loss of motor and sensory function due to interruption of the
blood supply through the anterior spinal artery.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 178.

78
Q

How is anterior spinal artery syndrome linked to

spinal anesthesia?

A

Prolonged hypotension due to a spinal anesthetic has been
linked as a causative factor in the development of ASAS.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 178.

79
Q

Why does anterior spinal artery syndrome not affect
the sense of vibration and proprioception in the
affected areas?

A

The anterior spinal artery supplies the anterior two-thirds of the
spinal cord. The nerves responsible for proprioception and
vibration sense are located in the posterior spinal cord.
Wong, CA. Spinal and Epidural Anesthesia. New York:
McGraw-Hill; 2007: 178.

80
Q

How does total spinal anesthesia occur and what are

its symptoms?

A

Total spinal anesthesia occurs when the local anesthetic
spreads throughout the subarachnoid space high enough to
block sympathetic outflow from the entire spinal cord and
possibly even the brainstem. It results in respiratory arrest,
profound hypotension, and bradycardia from sympathetic
blockade. Spinal blockade, even at the cervical level is
reported not to be high enough to block the large A-alpha fibers
of the phrenic nerve. Apnea appears to be the result of
decreased perfusion to the brainstem as apnea typically
resolves with hemodynamic resuscitation.
Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC,
Ortega R. Clinical Anesthesia. 7th ed. Philadelphia, PA:
Lippincott Williams and Wilkins; 2013: 927.

81
Q

How is total spinal blockade treated?

A

Respiratory support, vasopressors, IV fluids, and atropine are
administered as needed. If cardiopulmonary status is
maintained, a total spinal block is self-resolving as the block
recedes.
Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC,
Ortega R. Clinical Anesthesia. 7th ed. Philadelphia, PA:
Lippincott Williams and Wilkins; 2013: 927-928.

82
Q

What factors increase the risk for postdural puncture
headache (PDPH) when performing spinal
anesthetics?

A

The incidence of postdural puncture headache increases with
the use of non-pencil point needles, a cutting needle inserted
with the bevel of the needle perpendicular to the long axis of the
body, and multiple attempts. It is also more likely to occur in
young patients than elderly patients and more common in
female patients.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1085.

83
Q

How much epinephrine would you add to a spinal

anesthetic dose to prolong the duration of the block?

A

0.1 to 0.2 mL of 1:1000 (1 mg/mL) epinephrine is the dose
typically added to the local anesthetic to prolong the duration of
the spinal.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081.

84
Q

How does the addition of epinephrine comparatively
affect the duration of action of tetracaine, lidocaine,
and bupivacaine?

A

The addition of epinephrine prolongs the duration of tetracaine
the most, lidocaine moderately, and has almost no effect on the
duration of action of bupivacaine.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1081

85
Q

What opioids are typically added to subarachnoid

block injections and what doses are used?

A

Fentanyl 10-25 mcg, sufentanil 2.5-10 mcg, preservative-free
morphine 250 mcg, or even clonidine 150 mcg, all of which act
to prolong the duration of the spinal anesthetic.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1082.

86
Q

What is a saddle block?

A

A saddle block is a hyperbaric spinal anesthetic in which the
patient remains sitting after injection for 5 minutes so that the
local anesthetic can concentrate on the lumbar and sacral
nerves.
Nagelhout JJ, Plaus KL. Nurse Anesthesia. 5th ed. St. Louis,
MO: Elsevier Saunders Company; 2014: 1082.

87
Q

In what manner does a spinal block wear off?

A

A spinal block does not end abruptly, nor does sensation
throughout the affected dermatomes return at the same rate. A
spinal anesthetic recedes gradually from superior to inferior. As
a result, the sacral dermatomes demonstrate a longer duration
of action than do the lumbar or thoracic dermatomes.
Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC,
Ortega R. Clinical Anesthesia. 7th ed. Philadelphia, PA:
Lippincott Williams and Wilkins; 2013: 919.

88
Q

From shortest to longest, rank procaine, tetracaine,
bupivacaine, lidocaine, and chloroprocaine in order
of the duration of their spinal anesthetic when
equivalent dosages are administered.

A

Chloroprocaine and procaine are the shortest acting agents with
durations around 90-120 minutes. Lidocaine has a duration
around 140-240 minutes. Bupivacaine and tetracaine exhibit
durations around 240-380 minutes.
Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC,
Ortega R. Clinical Anesthesia. 7th ed. Philadelphia, PA:
Lippincott Williams and Wilkins; 2013: 919.

89
Q

A patient with a T8 sensory level following a spinal
anesthetic exhibits hypotension. Is this due to
dilation of venous or arterial vessels?

A

The sympathectomy associated with a spinal anesthetic
produces hypotension due principally to venous pooling from
dilation of the venous capacitance vessels, although arteriolar
dilation may contribute to the hypotension by a lesser degree.
Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s
Clinical Anesthesiology. 5th ed. New York, NY: McGraw-Hill;
2013: 946.