Pericardial Processes/Tamponade Flashcards

1
Q

What are the causes of acute pericarditis?

A

It is often due to a viral illness, but may often occur 1-3 days
after a myocardial infarction.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 144.

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2
Q

What are the symptoms of acute pericarditis?

A

Chest pain, pericardial friction rub, and a series of changes on
the ECG.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 144.

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3
Q

What is the volume of fluid that the pericardium can

normally hold?

A

15-50 mL
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 145

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4
Q

What are the treatments for acute pericarditis?

A

Non-steroidal anti-inflammatory drugs such as aspirin and
ketorolac are often used to treat the inflammation and oral
analgesics such as codeine may be used to treat the pain.
Corticosteroids are used in the treatment of pericarditis that
does not respond to these treatments.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 145.

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5
Q

What is Dressler’s syndrome?

A

Dressler’s syndrome is a form of pericarditis seen following
myocardial infarction.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 144

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6
Q

What are the symptoms of postcardiotomy

syndrome?

A

Postcardiotomy syndrome exhibits symptoms similar to acute
pericarditis. Causes include infection, autoimmune processes,
blunt or penetrating trauma, and occurs in 10-40% of patients
who have had cardiac bypass graft surgery involving
pericardiotomy. It occurs more frequently in pediatric patients.
It is not very common in cardiac transplant surgery and this is
believed to be due to immunosuppressant therapy. Cardiac
tamponade is rare in this syndrome.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 145.

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7
Q

What are the ECG changes seen with acute

pericarditis?

A

The ECG changes seen in acute pericarditis occur in four
stages. In stage I, there is diffuse ST segment elevation and
depression of the PR segment. In stage 2, the ST and PR
changes normalize. In stage 3, the T wave inverts, and in stage
4, the T waves normalize.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 144-145.

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8
Q

What factors tend to worsen and relieve acute

pericarditis?

A

Deep inspiration worsens the pain. It is often relieved by sitting
forward.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 144-145.

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9
Q

Does acute pericarditis alter cardiac function?

A

If no other associated pericardial disease is present, acute
pericarditis does not alter cardiac function.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 145.

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10
Q

What induction agents and adjuncts are most useful
for the patient with cardiac tamponade undergoing
general anesthesia?

A

Induction is typically carried out with ketamine because it
increases heart rate, contractility, and systemic vascular
resistance. A benzodiazepine is often combined with it. The
anesthetic may be maintained with nitrous oxide and fentanyl
combined with pancuronium, which is useful for its vagolytic
effects.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 148.

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11
Q

What is the difference between a pericardial effusion

and pericardial tamponade?

A

Pericardial effusion is the collection of fluid in the pericardial
cavity. Percardial tamponade occurs when the fluid collects to
a significant enough volume that cardiac contraction is impaired.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 145-146.

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12
Q

What are the causes of pericardial effusion?

A

It may occur from almost any pericardial disease process such
as infection, trauma, metastatic disease, mediastinal disease,
radiation, rheumatoid arthritis, systemic lupus erythematosus,
and scleroderma. About 20% of cases are idiopathic.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 145.

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13
Q

How does the volume of fluid necessary to produce
pericardial tamponade differ between acute and
chronic pericardial effusion?

A

An acute influx of as little as 100 mL into the pericardium can
produce a symptomatic tamponade. In chronic pericardial
effusion, symptoms may not become severe until the volume is
in excess of 2 liters.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 146.

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14
Q

How is right atrial pressure related to the severity of

cardiac tamponade?

A

As the pericardial pressure increases, the right atrial pressure
increases with it. Thus, the right atrial pressure becomes an
accurate reflection of the pericardial pressure. It is at the point
where the pericardial and right atrial pressures become equal
and the patient may begin to exhibit signs and symptoms of
tamponade.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 146.

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15
Q

What are Kussmaul’s sign and pulsus paradoxus?

A

Kussmaul’s sign is the distention of jugular veins during
inspiration. Pulsus paradoxus is a decrease in systolic blood
pressure greater than 10 mmHg during inspiration. Both of
these signs are consistent with a diagnosis of cardiac
tamponade.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 146

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16
Q

What is Beck’s triad?

A

Beck’s triad consists of quiet heart sounds, increased jugular
venous pressure, and hypotension and occurs in about 1/3 of
patients with acute cardiac tamponade.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 146.

17
Q

What is the most accurate means of diagnosing

cardiac tamponade?

A

Echocardiography, which can detect effusions as small as 20
mL
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 147

18
Q

What are the effects of general anesthesia and
positive pressure ventilation on the patient with
cardiac tamponade?

A

The combination of peripheral vasodilation and myocardial
depression from the anesthetic and decreased venous return
from positive pressure ventilation can produce severe, lifethreatening
hypotension in the patient with cardiac tamponade.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 148.

19
Q

What clinical signs would you expect to see in a

patient with constrictive pericarditis?

A

Constrictive pericarditis is similar to cardiac tamponade in many
of its features. They both exhibit pulsus paradoxus and
Kussmaul’s sign. Kussmaul’s sign is more common in patients
with constrictive pericarditis. Pulsus paradoxus is more
common in patients with tamponade. Constrictive pericarditis
also exhibits Freidreich’s sign, which is a prominent y-descent
on the central venous pressure tracing.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 148-149.

20
Q

What symptoms of cardiac tamponade are

indications of ventricular discordance?

A

Kussmaul’s sign and pulsus paradoxus are both indicative of
ventricular discordance (also known as ventricular
dyssynchrony) that occurs due to the opposing response of the
ventricles to filling during the respiratory cycle.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 146.

21
Q

What interventions would be appropriate in the
management of a patient with symptomatic cardiac
tamponade until a pericardiocentesis can be
performed?

A

The primary goals in the management of a patient with
symptomatic cardiac tamponade include: expanding
intravascular volume by administering crystalloids or colloids,
maintaining heart rate and contractility by administering
catecholamines (including isoproterenol), administering
dopamine to increase systemic vascular resistance if
necessary, administering atropine to prevent vagal reactions to
the increased intrapericardial pressure, and correcting
metabolic acidosis (metabolic acidosis can have detrimental
effects on cardiac contractility).
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 148.

22
Q

How is cardiac tamponade treated?

A

Mild tamponade can often be managed medically, but a
pericardiocentesis is the definitive treatment for acute
symptoms. If this cannot be performed immediately, then
temporizing measures include: increasing the intravascular
fluid volume, administering catecholamines to maintain
adequate contractility, and correction of acidosis.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 148

23
Q

What is constrictive pericarditis and what are its

causes?

A

Contrictive pericarditis is a fibrotic scarring of the pericardium
that diminishes the pericardial space and creates a rigid,
constrictive sac around the heart. It often occurs following
radiation therapy, tuberculosis, or previous cardiac surgery.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 148-149.

24
Q

What are the symptoms of myocardial contusion?

A

Chest pain, palpitations, dysrhythmias, ST and T wave
abnormalities, and elevated creatine kinase and troponin levels.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 151.

25
Q

Is the angina associated with myocardial contusion

relieved by nitroglycerin?

A

No.
Hines RL, Marschall KE. Anesthesia & Co-Existing Diseases.
6th ed. Philadelphia, PA: Elsevier-Saunders; 2012: 151.