Stroke Flashcards
What is stroke?
Rapidly developing clinical symptoms and/or focal signs, and at times global loss of brain function, with symptoms lasting more than 24h leading to death with no apparent cause other than vascular origin
STROKE is a diagnosis TRUE/FALSE
FALSE
It is not a diagnosis, it is the experience of persisting neurological complications of cardiovascular disease
Which score helps to diagnose strokes?
Rosier Score
What fraction of all stroke presentations are stroke mimics e.g. seizures?
1/3
A TIA as compared to a stroke is benign TRUE/FALSE
FALSE
It is not benign
What time frame do symtoms have to last for for it to be classed as a TIA rather than a stroke?
Less than 24h
Define TIA
A brief episode of neurological dysfunction caused by ischaemia with clinical symptoms typically lasting less then 1h and without evidence of acute infarction
Which age group is stroke most common in?
More common in elderly, peak incidence >70 but can occur in other age groups
Strokes are more common in females T/F
False
Stroke more common in males
What 4 things is the extent of damage determined by?
Arterial territory of the affected artery
Timescale of the occlusion
Extent of the circulatory relief
System perfusion pressure
Before how many hours is there very little to observe on microscopy/microscopy after a stroke?
Less than 12h
How many days post stroke does the brain become gelatinous and febrile?
2-14 days
How long post stroke does it take for microglia to become the predominant cell type?
2-14 days
How early does reactive gliosis begin?
As early as wk 1
A CT is excellent and always picks up bleeds in the brain TRUE/FALSE
It is rather excellent however if hyperacute it may be essentially normal and it is not sensitive to bleeds over 1 week old
MRI is good with stroke at identifying…
Old lesions
Those of non-vascular origin
What is the time limit on using IV tissue plasminogen activator?
<4.5h
Do not treat cardioembolic stroke with aspirin TRUE/FALSE
TRUE