Epilepsy and Seizures Flashcards

1
Q

What is a seizure?

A

A short episode of symptoms caused by a burst of abnormal electrical activity in the brain

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2
Q

What is epilepsy?

A

The ongoing liability to recurrent seizures

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3
Q

What can auras look like?

A

Deju-Vu

Change in smell, Vision orTaste

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4
Q

When are seizure most common?

A

Infancy and old age

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5
Q

Who are focal seizures more common in?

A

The elderly (Cortical abnormality)

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6
Q

If in a focal aware seizure there was motor signs such as stiffness, twitching or spasm which lobe of the brain would it most likely to located in?

A

The frontal lobe

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7
Q

What is a Jacksonian march?

A

A phenomenon where a focal aware seizure spreads from distal part of the limb towards the ipsilateral face

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8
Q

If in a focal aware seizure there was sensory manifestations such as tingling or numbness of pain what area of the brain is most likely affected?

A

Parietal lobe

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9
Q

If in a focal aware seizure there is visual phenomenon such as flashing lights, colours or hallucinations what is the likely lobe?

A

Occipital lobe

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10
Q

If in a focal aware seizure there is changes in mood/behaviour and a rising epigastric sensation then which lobe of the brain is it most likely in?

A

Temporal lobe

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11
Q

Focal impaired awareness seizures arise from which lobe in the majority of cases?

A

Temporal lobe

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12
Q

What is the most common cause of messiah temporal lobe epilepsy?

A

Hippocampal sclerosis

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13
Q

What are the 3 distinct components of complex partial seizures?

A

Aura
Abscence
Automitism

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14
Q

TRUE/FALSE

Awareness is always impaired on generalised seizures

A

TRUE

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15
Q

Where is the abnormality in generalised seizures?

A

Cortical network

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16
Q

What are the types of generalised seizure?

A
Absence
Myoclonic
Clonic
Tonic
Tonic-Clonic
Atonic
17
Q

With an absence seizure there is still post-ictal confusion TRUE/FALSE

18
Q

In what type of seizure are there 3 Hz generalised spike-waves?

A

Absence seizures

19
Q

When do juvenile myoclonic epilepsy seizures tend to occur?

A

First hour or so after wakening

20
Q

What age does juvenile myoclonic epilepsy tend to occur?

21
Q

What age do clonic seizures tend to occur?

A

Neonates/young children

22
Q

What drug in avoided in myoclonic seizures?

A

Carbamazepine

23
Q

Brief LOC, patient falls to the ground, often extension of the neck, upturning of the eyes and arching of the back is characteristic of which type of seizure?

A

Tonic seizure

24
Q

When his EEG indicated?

A

1-Classification of epilepsy
2-Confirmation of non-epileptic status
3-Surgical evaluation
4-Confirmation of non-convulsive status

25
What are some differentials of seizures?
``` Syncope TIAs Migraines Hypoglycaemia Tonic spasms of MS ```
26
Give anticonvulsants to all who present with seizures TRUE/FALSE
NAA, Whatcha playin | Only give drugs if they have epilepsy, do NOT GIVE DRUGS IF THEY PRESENT WITH A SINGLE SEIZURE
27
What is the first line treatment of absence seizures?
Ethosuximide
28
What is 1st line for focal seizures?
Lamotrigine or carbamazepine
29
What is the mode of action for sodium Valporate?
Na+ channel inactivation with increased GABA concentration
30
What anticonvulsant drug is used in pregnancy as it is not teratogenic?
Lamotrigine
31
What is Status epilepticus?
A convulsive seizure which continues for a prolonged period (5 minutes+) OR When convulsive seizures occur one after the other with no recovery inbetween
32
What is the treatment for status epileptics in the community v in hospital?
Community- Midazolam | Hospital-Lorazepam
33
What is some of the lasting damage that status epileptics can cause?
Respiratory insufficiency Hypotension Hyperthermia Rhabdomyolysis