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STIs Flashcards

1
Q

What is the commonest bacterial STI in the UK?

A

Chlamydia

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2
Q

Women with chlamydia are at high risk of developing PID. True/false?

A

False - 9%

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3
Q

A patient with chlamydia develops PID. Give two risks of this.

A

Ectopic pregnancy

Tubal infertility

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4
Q

How does chlamydia present in a female?

A

Bleeding - post-coital/intermenstrual
Lower abdo pain
Dyspareunia

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5
Q

How does chlamydia present in a male?

A

Urethral discharge
Dysuria
Urethritis
Epididymo-orchitis

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6
Q

Give some potential complications of chlamydia infection

A 
PID
Tubal damage
Chronic pelvic pain
Conjunctivitis
Reactive arthritis
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7
Q

How long after exposure should chlamydia be tested for?

A

14 days

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8
Q

What test is used to diagnose chlamydia and how is it taken in males/females?

A

NAAT
Females - vulvovaginal swab
Males - first void urine

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9
Q

When should a rectal swab for chlamydia be added?

A

Receptive anal intercourse

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10
Q

What is the treatment for chlamydia?

A

Doxycycline 100 mg twice daily for 1 week

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11
Q

How does gonorrhoea present in men?

A

Mucopurulent urethral discharge

Dysuria

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12
Q

How does gonorrhoea present in women?

A

Increased vaginal discharge
Dysuria
Pelvic pain

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13
Q

Give some potential complications of gonorrhoea

A 
Bartholinitis
Endometritis
PID
Rectal/periurethral abscesses
Prostatitis
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14
Q

What test is done to screen for gonorrhoea?

A

NAATs

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15
Q

What is the first-line treatment for gonorrhoea?

A

Ceftriaxone 500mg IM

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16
Q

When is test of cure carried out in patients with gonorrhoea?

A

2 weeks

17
Q

What are the incubation and duration periods of genital herpes?

A

Incubation - 3-6 days

Duration - 14-21 days

18
Q

Give some symptoms of primary genital herpes

A 
Blistering/ulceration of external genitalia
Pain
Dysuria
Discharge
Lymphadenopathy
19
Q

Recurrent episodes of genital herpes are more common with which HSV? Why?

A

HSV 2

Higher rates of viral shedding

20
Q

How do recurrent episodes of HSV present?

A

Unilateral small blisters and ulcers

21
Q

Outline the management of genital herpes

A

Swab base of ulcer for PCR
Oral acyclovir
Topical lidocaine

22
Q

When should you be very concerned about an episode of genital herpes?

A

First episode in 3rd trimester

23
Q

What is the most common viral STI in the UK?

A

HPV

24
Q

Give the main low and high risk HPV serotypes

A

Low risk - 6 & 11

High risk - 16 & 18

25
Q

How may HPV infection present?

A

Anogenital warts

26
Q

What treatment is available for genital warts?

A

Podophyllotoxin
Imiquimod
Cryotherapy - pregnancy

27
Q

The HPV vaccine covers which serotypes?

A

6, 11, 16 and 18

28
Q

What bacterium causes syphilis?

A

Treponema pallidium

29
Q

What are the stages of acquired syphilis infection?

A 
Primary
Secondary
Early latent
Late latent
Tertiary
30
Q

What is the average incubation period of primary syphilis infection?

A

21 days

31
Q

How does primary syphilis infection classically present?

A

Primary painless chancre

32
Q

Give some clinical features of secondary syphilis

A

Macular/follicular rash
Mucous membranes lesions
Lymphadenopathy
Condylomata lata

33
Q

What test is usually done to diagnose syphilis?

A

PCR

34
Q

What can be done to test for antibodies to pathogenic treponemes?

A

Serological testing

35
Q

What is the main serological screening test for treponema?

A

ELISA

36
Q

How is syphilis treated?

A

2.4 MU benzathine penicillin

37
Q

How is syphilis followed up serologically?

A

Testing RPR titres to see if they decrease

Reproduction (33 decks)

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