Prescribing in Pregnancy

Question 1

What is pharmacokinetics?

Answer 1

What the body does to the drug

Question 2

What is pharmacodynamics?

Answer 2

What the drug does to the body

Question 3

Which is more affected in pregnancy - pharmacokinetics or pharmacodynamics?

Answer 3

Pharmacokinetics

Question 4

What drug should all women planning to become pregnant be prescribed?

Answer 4

Folic acid 400mcg daily

Question 5

Medication is generally okay to take in the 1st trimester. True/false?

Answer 5

False - should try avoid if possible

Question 6

Give some examples of teratogenic drugs

Answer 6

ACEIs/ARBs
Antiepileptics
Cytotoxics
Lithium
Methotrexate
Retinoids
Warfarin

Question 7

What treatment should be aimed for in a pregnant woman with epilepsy?

Answer 7

Monotherapy
Avoid valproate/phenytoin
Folic acid 5mg daily

Question 8

Is insulin thought to be safe during pregnancy?

Answer 8

Yes

Question 9

What drugs are used to treat hypertension in pregnancy?

Answer 9

Labetalol
Methyldopa
Nifedipine MR

Question 10

What drug can be used to treat nausea and vomiting in pregnancy?

Answer 10

Cyclizine

Question 11

What drug should be given to woman with significant risk factors for VTE?

Answer 11

LMWH

Question 12

What drugs should be avoided in women who are breastfeeding?

Answer 12

Amiodarone
Cytotoxics
Benzodiazepines
Bromocriptine