Antenatal Care and Screening Flashcards

1
Q

How is sensitivity of a screening test calculated?

A

True positive / (positive + false negative)

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2
Q

How is specificity of a screening test calculated?

A

True negative / (negative + false positive)

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3
Q

Which investigations are carried out at the booking visit?

A
Hb
Rhesus
Syphilis; HIV; Hep B&C
Urinalysis
USS
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4
Q

How does the clinician know if the pregnancy is continuing?

A

If they can see a heart on USS

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5
Q

What should be suspected if there is no embryo in the uterus?

A

Ectopic pregnancy

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6
Q

Which syndromes can be picked up as part of screening for Down’s?

A

Edwards’ and Patau’s

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7
Q

Edwards’ syndrome is trisomy 18. True/false?

A

True

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8
Q

Patau’s syndrome is trisomy 16. True/false?

A

False - trisomy 13

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9
Q

What occurs in placenta praevia?

A

When the placenta is low lying in the womb and covers all/part of the cervix

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10
Q

What tests can be done to assess the risk of Down’s in the first trimester?

A

Nuchal translucency

Beta-HCG

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11
Q

What blood tests are done to assess risk of Down’s in the second trimester?

A

Assay of HCG and AFP

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12
Q

What specific diagnostic tests are done for Down’s syndrome?

A

Amniocentesis

Chorionic villus sampling

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13
Q

What is the main risk of amniocentesis and chorionic villus sampling?

A

Miscarriage

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14
Q

What major haemotological disorders are screened for in antenatal care?

A

Sickle cell disease

Thalassemias

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15
Q

Women with which risk factors should be offered screening for gestational diabetes?

A

BMI >30
Previous baby weighing >4.5kg
Previous gestational diabetes
FHx of diabetes

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16
Q

Which measurement is made to assess foetal growth?

A

Symphysis fundal height

17
Q

Give some high risk factors for pre-eclampsia

A
Previous pre-eclampsia
CKD
Autoimmune disease (SLE/APS)
T1/2DM
Hypertension
18
Q

Give some moderate risk factors for pre-eclampsia

A
First pregnancy
Age >40
BMI >25 
FHx of pre-eclampsia
Multiple pregnancy
19
Q

Women at risk of pre-eclampsia should be treated with what?

A

75mg aspirin