Stimulants Flashcards

1
Q

what is Ma Huang?

A

chinese herb from the ‘horsetail’ plant

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2
Q

when was the earliest documentation of ma huang?

A

3000 BC

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3
Q

what is the active ingredient in ma huang?

A

ephedrine

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4
Q

what effect does ephedrine have on the lungs?

A

its a broncodialator, so used for nasal decongestion and asthma

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5
Q

what drug is produced illegally from legal obtaining of ephedrine?

A

methamphetamine

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6
Q

what products were ephedrine found in before it was banned?

A

weight loss, helps burn fat bc it regulates body temp

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7
Q

what is khat?

A

from the catha edulis plant in africa

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8
Q

what form was the early use of khat?

A

Abyssinian tea

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9
Q

what is the active ingredient in khat?

A

cathinone

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10
Q

what are the effects of chewing khat leaves?

A

feeling content, not tired, anorexia, mental stim

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11
Q

when was khat made illegal?

A

1997

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12
Q

what is methcathinone?

A

a modified version of the active ingred. in khat (cathinon)

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13
Q

why was methcathinone synthesized?

A

soviet russia wanted to use it to treat depression or abuse

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14
Q

what is the street name for methcathinone?

A

cat

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15
Q

what is the main effect from methcathinone?

A

euphoria

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16
Q

what is the consumption pattern of methcathinone users?

A

binge for several days without eating or sleeping, then crashing for several days following and repeat

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17
Q

what drug is methcathinone similar to abuse-wise?

A

methamphetamine

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18
Q

does use of methcathinone damage neurons?

A

yes, it damages dopaminergic neurons

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19
Q

what is the most recently famous synthetic cathinone?

A

bath salts

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20
Q

what are the most popular synthetic cathinones?

A

mephedrone and methylenedioxypyrovalerone (MDPV)

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21
Q

what is the main term used to describe effects of synthetic cathinones?

A

‘excited delirium’

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22
Q

where does the coca plant originate from?

A

central america and south america

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23
Q

which indigenous culture chewed coca plants regularly?

A

the inca

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24
Q

when spanish conquerors arrived, what did they think of coca chewing?

A

that it was bad bc it created bonds for the indigenous people and thought it was a pagan ritual

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25
why did the spanish eventually allow the chewing of coca?
native people could work longer and needed less food when chewing coca
26
who isolated cocaine from the coca plant?
Niemann, 1859
27
why did coca not take well in europe until cocaine was isolated?
only way to get coca was chewing w wasnt popular, once cocaine was isolated it could be added to drinks like they preferred (suited the culture there)
28
what was freud's opinion of cocaine?
initially thought it was great and showed everyone, but later on disapproved bc he saw how it ruined lives
29
what is vin mariani?
a cocaine infused french wine
30
who created vin marian in 1863?
angelo mariani, a corsican businessman
31
who created an imitation of vin mariani in 1885 and what was it called?
Pemberton, French wine cola
32
what product followed the creation of french wine cola?
Coca cola (soda water + kola nut instead of wine)
33
are coca leaves still used in the production of coca cola?
yes! but they are decocainized since 1906
34
are coca leaves still used in the production of coca cola?
yes! but they are decocainized since 1906
35
when did the anti-drug sentiment begin
1900s
36
what was the ethnic association with drugs?
if an ethnic minority used a drug, the drug is dangerous and should be banned
37
what government legislation was introduced on medicine in 1906?
pure drug and food act, required list of ingredients on medicine (big pharma was sad)
38
when was cocaine included in drug legistlation?
1911, it missed the first legistlation that was in 1908
39
what was the time article about the white goddess about?
a cuban official being part of the cocaine dealings in the 1950s
40
what was the peak time range that cocaine was #1 stimulant drug?
1970s to 1980s
41
why was there such a peak in cocaine production and distribution in the 70s/80s?
better organized drug growers and traffickers, lax south american govt
42
what was the 5 years that cocaine abuse admission was at its peak?
1975 to 1980
43
why was cocaine so sought after?
seen as the 'cadillac' of drugs aka famous ppl use it
44
when did crack emerge?
1980s, lots of media attention
45
why is crack named crack?
because of the popping noise that the lil rocks make when smoked
46
why is crack different than cocaine?
cocaine doesnt do well with heat so you cant smoke it, it has to be injected or snorted. crack has higher temperature resistance so can be smoked
47
why is crack more sought after than cocaine?
because you can smoke it, you get a stronger and faster high (but also shorter lived) and you dont have to do injections
48
how many pounds of coca leaves is needed to make 1 pound of cocaine?
400 lbs of leaves
49
how is coca paste made?
extract cocaine from coca leaves and kerosene is added to float it to the top where its skimmed off
50
what is the % purity of coca paste?
60% pure cocaine
51
how is coca paste turned into 99% pure white powder?
treated by acids and oxidizing stuff to make cocaine hydrochloride (99% cocaine)
52
what is the name of the 99% pure white powder cocaine?
cocaine hydrochloride
53
how is crack derived from cocaine hydrochloride?
treat it w alkaline solution that separates the salt from the cocaine, therefore making it lil smokable rocks
54
what is the biggest difference between crack and cocaine hydrochloride?
the method of administration (effects are relatively the same)
55
why was amphetamine synthesized in 1887?
sought it to be a replacement for the natural stim. ephedrine
56
when was methamphetamine synthesized?
1919
57
when were amphetamines incorporated into society and medicine?
not until 1930s
58
what was benzedrine marketed as?
it was a nasal inhaler treatment for asthma and nasal congestion, contained amphetamine to act similar to ephedrine
59
what public transit system sold benzedrine inhalers without prescription?
airlines
60
when was amphetamine available in tablet form?
1937
61
what was tablet form amphetamine's trade name
Dexedrine
62
what was dexedrine treatment for?
narcolepsy, weight loss, ADD
63
how were benzedrine inhalers abused?
the cloth containing benzedrine was removed and chewed, brewed, or bagged like a solvent
64
why did amphetamine appear a good time for drug users?
prohibition was just ending and cocaine was not as popular since the 20s
65
what was the college nickname for amphetamine tablets?
pep pills, pepper uppers - to be taken for studying or during exams
66
who in ww2 took methamphetamine?
hitler
67
which country experienced a big boom in amphetamine following ww2?
japan had a surplus so sold it = high lvl of use
68
what year did they initiate requiring a medical prescription for amphetamine meds?
1965
69
when was amphetamine listed as a bad drug?
1971
70
what was the consumption method of amphetamine in EARLY use?
oral or inhalation
71
what area of san fran. did injection of amphetamine start u in the 60s?
Haight Ashbury district
72
what is speedball?
the combo of heroin and another stimulant (cocaine or amphetamine or methamphetamine)
73
what does NIU stand for?
non injection forms of use
74
what is more -vely perceived? injection or non injection use?
injection is more -ve
75
what contributed to the -ve perception of amphetamine?
distrib. of drug assoc with motorcycle gangs, and medical knowledge that chronic amphetamine use = psychosis and aggression
76
what does speed freak mean?
indv that were psychotic and aggressive due to amphetamine use
77
what is phenmetrazine?
an antiobesity drug that temporarily replaced amphetamines on its popularity decline
78
what eventually replaced the distaste with amphetamines?
cocaine aka the white goddess
79
what is the street name of phenmetrazine?
bam
80
why is amphetamine/methamphetamine popular again since the 90s?
ease of supply- can be easily made from chemicals available here
81
can cocaine be produced in canada?
nope must be smuggled into country
82
what is a street name for methamphetamine?
crank or ice
83
what does the gay community call methamphetamine?
tina - assoc. w unsafe sex and needle sharing