Cannabis Flashcards
what is the street name for cannabis?
marijuana
what are the 3 types of cannabis plant?
sativa, indica, ruderalis
what are cannabinoids?
unique chemical agents found in the cannabis plant
t/f: cannabis is the oldest cultivated plant used for food
false; it is oldest plant NOT used for food
when/where was cannabis first recorded use?
China, 2800 BC
when did cannabis spread to Europe?
early 1800’s (bc of british colonization)
who was Harry Anslinger?
a campaigner against weed that brought attention to the drug in the 20’s in the US
how were marijuana laws justified early on?
that ethnic minorities were main users, therefore negative association
what year was cannabis classified as a narcotic and introduced into legislation?
1929
what is the active ingredient in weed?
delta-9-tetrahydrocannabinol (THC)
when was THC isolated & synthesized?
1964
what is the proportion of THC content in a typical joint from the 70s and now?
today’s weed has double the THC content
what is hashish?
the dried resin of the flowers/leaves of the plant
what is the THC % in hash?
10% THC
what is the THC % in hash oil
40% THC
how is hash oil made?
boil hashish in solvent (alcohol) to extract cannabinols
what is the most typical method of taking weed?
smoking a joint
what are other options of smoking weed?
using a bong or hookah (pipe like devices that filter smoke with water)
what is sensitization of marijuana?
when users do not experience effects of THC the first few times bc theyre not effecient at extracting THC from smoke
how much of THC in a joint is available for absorption?
less than 50%
what is the scientific justification for sensitization of weed?
users become better at smoking the more they do it ie. get better and larger dose of the drug as they smoke more
what is the onset time of effects from smoking?
within seconds
what is the peak blood concentration time from smoking?
10 minutes after inhalation
when do peak effects occur from smoking?
30-60 minutes
how long do effects normally last from smoking?
2-4 hours
what is the half life of THC?
around 5 days
are cannabinoids water or lipid soluble?
lipid soluble -cross blood-brain barrier easily
how long can THC be drug tested in the body?
several days to several weeks afterwards (THC deposits in fat and re-enters circulation during long half life)
are cannabinoids absorbed well in the digestive system?
no, only 20% enters bloodstream
whats the ratio between edibles and smoking effect vs dose?
need 3 doses of edibles to get same effect of 1 dose of smoking
when do peak effects of edibles occur?
1-3 hours after ingestion
what effect does a low dose (1/4- 1/2 joint) produce?
mild euphoria, peacefulness
what effect does moderate (1 joint) dose produce?
perception and time distortions, drowsiness
what effect does a high dose (2 joints) produce?
hallucinations, delusions, distortions of body image
what are the physiological effects?
bloodshot eyes, droop in eyelids, dry mouth/thirst, hunger/overeating
does cannabis have an effect on pupil dialation?
no, it is a result of smoking in dark lighting
what is the effect of placebo and expectations of weed?
large effect of expectations on ratings of weed
t/f: weed can be used as an aphrodisiac (increase libido)
true, induces brief rise of testosterone
- but only at low doses.
- at high doses, it depresses testosterone levels and creates orgasmic difficulty
what is the name of the sesame oil THC medical product?
dronabinol, trade name marinol
what is the synthetic form of THC medical product?
nabilone, trade name cesamet
what is the THC oral spray used for MS?
Sativex
t/f: THC is not antiemetic (reduces vomiting)
false, it is antiemetic
what is more effective as anti-nausea/vomiting? medical products vs smoking product?
medical products like marinol and cesamet are better
is natural or man made (dronabinol) weed more effective as a pain killer?
dronabinol has longer pain relief effects