Steroids Flashcards
name the carbons
cortisol
aldosterone
progesterone
testosterone
17 beta estradiol
progesterone
female menstrual cycle, pregnancy, embryogenesis
17 beta estradiol
estrogen, female hormone
testosterone
androgen, male hormone
cortisol
glucocorticoid, anti-stress hormone, anti-inflammation
aldosterone
mineralocorticoids, regulator Na uptake in kidney, raises blood volume and blood pressure
17 alpha hydroxylase deficiency
adrenal hyperplasia (5%), overproduction mineralcorticoids, sex hormone deficiency, hyperaldosteronism
21 hydroxylase deficiency
adrenal hyperplasia (95%), hirsutism, early epiphyseal closure, hypoaldosteronism
aminoglutethimide (action/use)
inhibits aromatase and P450scc
used to block steroid production in some hormone-dependent tumors (breast, prostate)
aminoglutethimide