ANS Overview Flashcards
primary neurotransmitter of preganglionic neurons
ACh
neurotransmitter of postganglionic PSNS
ACh
neurotransmitter of postganglionic SNS
norepinephrine
preganglionic PSNS neurons length
long
postganglionic PSNS neurons length
short
preganglionic SNS neurons length
short
postganglionic SNS neurons lenth
long
sweat glands exception
SNS post ganglionic neurons release NE with sweaty palms, normally is thermoregulation in PSNS and release ACh
adrenal glands exception
preganglionic do not synapse in paravertebral, release epinephrine instead of norepinephrine
kidneys exception
affected by dopamine
most postganglionic sympathetic neurons release which neurotransmitter?
norepinephrine
classes of cholinoceptors and respective neurotransmitter (s)
muscarinic and nicotinic, acetylcholine
classes of adrenoceptors and respective neurotransmitter (s)
alpha and beta, norepinephrine and epinephrine
nicotinic receptors
ganglionic, skeletal muscle, neuronal CNS
nicotinic signal transduction pathway
Na+ ion channels
M1 signal transduction pathway
Gq, increase PLC, second messengers DAG and IP3, increase intracellular Ca levels
M2 signal transduction pathway
Gi, inhibit AC, second messenger cAMP
alpha 1 signal transduction pathway
Gq, stimulate PLC, second messengers DAG and IP3, increase intracellular Ca levels
alpha 2 signal transduction pathway
Gi, inhibit adenyl cyclase, second messenger cAMP
beta 1-3 signal transduction pathway
Gs, stimulate adenyl cyclase, second messenger cAMP
who proposed the tale of two transmitters
Sir Henry Dale
which sites are predominantly sympathetic?
arterioles, veins, sweat glands
muscle on inner part of eye
circular muscle
muscle on outer part of eye
radial muscle
