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PHRM 825 > GI Pharm > Flashcards

GI Pharm Flashcards

1
Q

AlternaGEL

A

aluminum hydroxide Al(OH)3

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2
Q

Tums

A

calcium carbonate CaCO3

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3
Q

Maalox, Mylanta

A

aluminum hydroxide and magnesium hydroxide

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4
Q

Rolaids

A

calcium carbonate and magnesium hydroxide

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5
Q

Alka-Seltzer

A

aspirin and sodium bicarbonate

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6
Q

Gaviscon

A

aluminum hydroxide and magnesium carbonate

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7
Q

cimetidine (tagamet)

A

competitive antagonist of H2R

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8
Q

Zantac

A

ranitidine

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9
Q

Axid

A

nizatidine

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10
Q

Pepcid

A

famotidine

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11
Q

Prilosec

A

omeprazole

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12
Q

Nexium

A

esomeprazole (more potent)

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13
Q

Prevacid

A

lansoprazole

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14
Q

Aciphex

A

rabeprazole

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15
Q

Protonix

A

pantoprazole

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16
Q

Dexilant

A

dexlansoprazole

17
Q

which class of drugs are prodrugs that must be protonated to become active?

A

PPIs

18
Q

-azole

A

PPi

19
Q

-idine

A

H2RA

20
Q

vonoprazan

A

potassium competitive acid blocker (PCAB)

21
Q

what types of bonds do PPIs do

A

covalent

22
Q

Cyotec

A

misoprostol

23
Q

Metamucil

A

psyllium

24
Q

Citrucel

A

methylcellulose

25
Q

fiberCON

A

calcium polycarbophil

26
Q

MiraLAX

A

PEG 3350

27
Q

Duphalac

A

lactulose

28
Q

peripheral opioid antagonists

A

Naloxegol, ALvimopan, Naldemedine

29
Q

metoclopramide

A

D2 dopamine receptor antagonist that increases Ach release for constipation

30
Q

metoclopramide

A

D2 dopamine receptor antagonist that increases Ach release for constipation

31
Q

prucloprade (Montegrity)

A

5HT serotonin agonist, chronic idiopathic constipation in adults

32
Q

lubiprostone (Amitiza)

A

activates type 2 chloride efflux channels

33
Q

Linzess

A

linaclotide, cGMP chloride channels

34
Q

Trulance

A

plecanatide, cGMP, chloride channels

35
Q

Tenapanor

A

Na/H exchanger leads to increased water in lumen

PHRM 825 (24 decks)

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