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PHRM 825 > EXAM 5 > Flashcards

EXAM 5 Flashcards

1
Q

alopecia treatment options

A

minoxidil and finasteride

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2
Q

finasteride

A

1 mg PO qd, continuously
SE: decreased libido, ED, decreased volume ejaculate
AVOID WITH WOMEN

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3
Q

minoxidil

A

apply 2 times a day every day, continuously
may take 4 months to see effects
apply to DRY scalp

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4
Q

testicular cancer treatment

A

surgery (orchiectomy)
radiation
chemotherapy

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5
Q

testosterone capsules

A

Jatenzo
158 to 396mg BID with food
measure serum levels 6 hours after AM dose

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6
Q

contraindications to testosterone therapy

A

prostate cancer, breast cancer, hematocrit > 50%, baseline PSA > 4 ng/dl or > 3 ng/ml in men at high-risk prostate cancer, recent or poorly controlled CVD

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7
Q

sildenafil brand name

A

Viagra

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8
Q

sildenafil starting dose and max dose

A

starting 50mg, max 100mg
starting dose 25mg if older than 65, hepatic impairment, CrCl less than 30

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9
Q

sildenafil duration

A

4 hours

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10
Q

tadalafil brand name

A

Cialis

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11
Q

tadalafil starting dose and max dose

A

starting 10mg but 2.5-5 mg if daily, max 200mg

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12
Q

tadalafil is also indicated for

A

BPH

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13
Q

tadalafil duration

A

36 hours

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14
Q

PDE 5 inhibitors precautions

A

oral or transdermal nitrates, alpha blockers, severe CAD, report erections lasting longer than 4 hours

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15
Q

pulmonary hypertension dose of tadalafil

A

40 mg daily

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16
Q

pulmonary hypertension dose of sildenafil

A

20 mg TID

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17
Q

alprostadil injection starting dose and max

A

2.5-10 mcg, max 60 mcg

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18
Q

tadalafil dose for BPH

A

5 mg daily

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19
Q

tadalafil dose CrCl less than 30

A

DONT USE!

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20
Q

tadalafil dose CrCL 30-50

A

2.5mg daily

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21
Q

finasteride dose for BPH

A

5mg daily

22
Q

dutasteride dose for BPH

A

0.5mg daily

23
Q

HPV vaccine ages and dosing

A

ages 9-14, 0, 6-12 months
ages 15+ 0, 1-2 months, 6 months

24
Q

etonogestrel implant side effect

A

irregular bleeding first 6-12 months

25
Q

hormonal IUD side effect

A

lighter and less frequent periods

26
Q

copper IUD side effect

A

periods heavier or stay same

27
Q

medroxyprogesterone shot fertility

A

delayed return

28
Q

very low dose estrogen

A

20 mcg EE + progestin

29
Q

low dose estrogen

A

30-35mcg EE + progestin

30
Q

high dose estrogen

A

50 mcg EE + progestin

31
Q

mini pill - norethindrone pill administration

A

within 3 hours of same time, no placebo pills, if late for dose use backup for 2 days

32
Q

disposable vaginal ring estrogen component

A

15mcg EE

33
Q

reusable vaginal ring estrogen component

A

13mcg EE

34
Q

norelgestromin patch efficacy

A

caution with BMI greater than 30, less effective if more than 198 lbs

35
Q

drugs causing amenorrhea

A

prochlorperazine, chlorpromazine, haloperidol, risperidone, verapamil, metoclopramide

36
Q

tranexamic acid dose

A

1,300mg PO TID x 5 days

37
Q

tranexamic acid CI

A

DVT, PE, seizure

38
Q

PMS diagnosis

A

at least 1 symptom for 3 menstrual cycles

39
Q

PMDD diagnosis

A

at least 5 symptoms, at least one in 2 different criteria for 2 months

40
Q

first line PMDD/PMS

A

SSRIs, NSAIDs, spironolactone

41
Q

SSRIs for PMDD/PMS

A

fluoxetine 20mg, sertraline 50-150mg, paroxetine 12.5-25mg

42
Q

spironolactone dosing for PMS

A

100mg days 15-28

43
Q

second line PMS/PMDD

A

SNRIs, COCs, clomipramine, alprazolam

44
Q

SNRIs PMDD/PMS

A

duloxetine 60, venlafaxine 75-112mg luteal or 50-200 daily

45
Q

mechanisms of PCOS

A

inapropriate gonadotropin secretion, insulin resistance, excessive androgen production

46
Q

criteria for PCOS (need two of three)

A

hyperandrogenism, polycystic ovaries, chronic anovulation

47
Q

cycle irregularity PCOS treatment

A

COC, cyclic progestin therapy

48
Q

hirsutism and hyperandrogenism in PCOS therapy

A

COC, spironolactone, finasteride, topical Vaniqa

49
Q

induction of ovulation PCOS

A

letrozole, GnRH therapy

50
Q

letrozole dosing

A

start at 2.5 then increase by 2.5 every cycle, max 5 cycles

PHRM 825 (24 decks)

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