staphylococcus aureus Flashcards

1
Q

is staphylococcus aureus hospital acquired

A

yes

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2
Q

what is a nosocomial infection

A

infections originating in hospital

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3
Q

what are hospital acquired infections

A

infections that are not present at the time of admission but occur in patient during admission

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4
Q

what gram is S. Aureus

A

positive

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5
Q

how does s.auereus establish an infection in terms of adhesion, invasion and biofilm formation

A

adhesion: has several adhesion proteins that aid bacterial attachment to host cell surface
invasion: where there is a breach in epithelial cells, S.aureus can penetrate to the deeper layers of tissue

biofilm formation: forms biofilms which antibiotics cannot penetrate

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6
Q

what is the percentage of people who have S.aureus naturally on their skin?

A

30

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7
Q

what are the types of infections s.aureus causes

A

skin and soft tissue infections
bone & joint
infection of the heart valves

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8
Q

is s.aureus resistant to antibiotics?

A

extremely yes

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9
Q

why is S.aureus highly resistant to antibiotics

A

biofilms and can modify the drug target for beta-lactam and vancomycin

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10
Q

how can we treat s.aureus

A

vancomycin

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11
Q

what are the two methods s.aureus is spread

A

endogenously and exogenous

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12
Q

what is endogenously

A

a patient already colonised can spread to other parts of their body

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13
Q

what is exogenous

A

person to person by direct contact

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14
Q

how can we prevent s.aureus

A

practising hand hygiene, covering wounds and lesions, using PPE

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