staphylococcus aureus Flashcards
is staphylococcus aureus hospital acquired
yes
what is a nosocomial infection
infections originating in hospital
what are hospital acquired infections
infections that are not present at the time of admission but occur in patient during admission
what gram is S. Aureus
positive
how does s.auereus establish an infection in terms of adhesion, invasion and biofilm formation
adhesion: has several adhesion proteins that aid bacterial attachment to host cell surface
invasion: where there is a breach in epithelial cells, S.aureus can penetrate to the deeper layers of tissue
biofilm formation: forms biofilms which antibiotics cannot penetrate
what is the percentage of people who have S.aureus naturally on their skin?
30
what are the types of infections s.aureus causes
skin and soft tissue infections
bone & joint
infection of the heart valves
is s.aureus resistant to antibiotics?
extremely yes
why is S.aureus highly resistant to antibiotics
biofilms and can modify the drug target for beta-lactam and vancomycin
how can we treat s.aureus
vancomycin
what are the two methods s.aureus is spread
endogenously and exogenous
what is endogenously
a patient already colonised can spread to other parts of their body
what is exogenous
person to person by direct contact
how can we prevent s.aureus
practising hand hygiene, covering wounds and lesions, using PPE