principles of pandemics Flashcards

1
Q

what causes changes in influenza

A

antigen drift and antigen shift

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2
Q

is the bubonic plague a zoonotic disease

A

yes

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3
Q

how is quarantine determined

A

incubation period, infectious period and changes on the disease

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4
Q

what is the prioritisation criteria for pathogens

A
  1. human transmission
  2. medical countermeasures
  3. severity
  4. human/animal interface
  5. public health context
  6. potential societal impacts
  7. evolutionary potential
  8. other factors
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5
Q

why are pathogens increasing with pandemic potential?

A
  1. global travel
  2. urbanisation
  3. climate change
  4. increased human animal contact
  5. health worker shortage
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6
Q

what makes a disease severe

A

transmissibility and case fatality risk

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7
Q

what are the stages of a pandemic

A
  1. no known cases
  2. few cases or clusters
  3. widespread community transmission
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8
Q

what are the stages of an emergency response

A
  1. Prevention
  2. Preparedness
  3. Response
  4. Recovery
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9
Q

what are examples of case-based interventions

A

testing and contact tracing, rapidly detect and isolate cases

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10
Q

what are examples of population-based interventions

A

face masks, physical distancing, work from hone

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11
Q

what are the stages of vaccine development

A

Discovery: development of the vaccine
Phase 1: given to a small group of healthy people
Phase 2: determine safety effectiveness
Phase 3: safety and effectiveness, dose, side effects
Regulatory: review and approval
Phase 4: surveillance for adverse events

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