principles of pandemics Flashcards
what causes changes in influenza
antigen drift and antigen shift
is the bubonic plague a zoonotic disease
yes
how is quarantine determined
incubation period, infectious period and changes on the disease
what is the prioritisation criteria for pathogens
- human transmission
- medical countermeasures
- severity
- human/animal interface
- public health context
- potential societal impacts
- evolutionary potential
- other factors
why are pathogens increasing with pandemic potential?
- global travel
- urbanisation
- climate change
- increased human animal contact
- health worker shortage
what makes a disease severe
transmissibility and case fatality risk
what are the stages of a pandemic
- no known cases
- few cases or clusters
- widespread community transmission
what are the stages of an emergency response
- Prevention
- Preparedness
- Response
- Recovery
what are examples of case-based interventions
testing and contact tracing, rapidly detect and isolate cases
what are examples of population-based interventions
face masks, physical distancing, work from hone
what are the stages of vaccine development
Discovery: development of the vaccine
Phase 1: given to a small group of healthy people
Phase 2: determine safety effectiveness
Phase 3: safety and effectiveness, dose, side effects
Regulatory: review and approval
Phase 4: surveillance for adverse events