cell biology of viruses

Question 1

what is a virion

Answer 1

entire virus particle

Question 2

what is the function of the capsomere protein

Answer 2

protect and cover the virion

Question 3

what classification scheme do we use to clarify viruses?

Answer 3

Baltimore

Question 4

how do retroviruses proliferate

Answer 4

they reverse transcribe, using reverse transcriptase, makes a complimentary DNA strand which them makes a double stranded DNA which can enter the genome as a template

Question 5

what is attachment

Answer 5

virion attaches to the cell

Question 6

what is penetration and uncoating

Answer 6

virion enters the host cell, loses the code

Question 7

what is Assembly

Answer 7

component parts of the virion is assembled into a completed virion

Question 8

how does influenza exit the nucleus

Answer 8

budding

Question 9

what steps happen during the viral gene expression and replication

Answer 9

1. The segmented viral genome is made up of -RNA.

2. Antigenomes are perfect copies of -RNA but lacking 5’ cap found in mRNA

Question 10

what are antigenomes used for

Answer 10

viral replication

Question 11

what is viral assembly

Answer 11

interactions between viral structures and the viral genome

Question 12

what is a prophage

Answer 12

a material of a bacteriophage incorporated into the genome and is able to produces phages

Question 13

what is lytic reproduction

Answer 13

involves the reproduction of viruses using a host cell to manufacture more viruses

Question 14

what is an example of a latent infection

Answer 14

herpes

Question 15

what is the infectious dose

Answer 15

number of viruses needed to cause an infection

Question 16

what is used to identify a virus

Answer 16

affinity chromtography

Question 17

what is the most common method of penetrating and uncoating

Answer 17

C. endocytosis of the virus followed by release of the nucleocapsid into the cytoplasm, no spike proteins are left on cell surface.

Question 18

what is actins involvement in the transport of viruses

Answer 18

important for the uptake of the virus into the host cell

Question 19

what is kinesins involvement in the transportation of viruses

Answer 19

for when a virus needs to leave a cell

Question 20

what is dyneins involvement in the transportation of viruses

Answer 20

carries protein until injected into a nuclear pore.

Question 21

what are bacteriophages

Answer 21

viruses that can infect and kill bacteria without any negative effect on human or animal cells