Spring Top 200 Final Flashcards

1
Q

atorvastatin

A

Lipitor, Caduet (combo product).
HMG-CoA Reductase Inhibitor.
Dyslipidemia.
BBW: N/A

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2
Q

omega-3-polyunsaturated fatty acids

A

Lovaza.
Antilipemic Agent, Omega-3 Fatty Acids.
Hypertriglyceridemia.
BBW: N/A

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3
Q

furosemide

A

Lasix.
Loop Diuretic.
Edema in HF, HTN, acute pulmonary edema
BBW: Fluid & Electrolyte Depletion

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4
Q

hydrochlorothiazide

A

Microzide.
Thiazide Diuretic.
HTN & edema
BBW: N/A

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5
Q

clonidine

A

Catapres, Catapres-TTS.
Alpha2 Agonist.
HTN
BBW: The 500 mcg/mL strength product should be diluted prior to use in an appropriate solution (injectable form).

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6
Q

metoprolol succinate

A

Toprol XL. BB.
Angina pectoris, HTN, or hemodynamically-stable acute MI.
BBW: Avoid abrupt cessation in ischemic heart disease

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7
Q

carvedilol

A

Coreg, Coreg CR.
BB with Alpha1-Blocking Activity
Indication: Mild-to-severe heart failure
BBW: N/A

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8
Q

amlodipine

A

Norvasc, Caduet (combo product), Lotrel (combo product).
CCB (Dihydropyridine).
HTN, angina.
BBW: N/A

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9
Q

diltiazem

A

Cardizem CD, Cardizem SR, Cartia XT.
CCB (Nondihydropyridine).
HTN, angina.
BBW: N/A

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10
Q

lisinopril

A

Zestril, Prinivil.
ACEI.
HTN, HF, MI.
BBW: fetal toxicity

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11
Q

digoxin

A

Digitek, Lanolin.
Antiarrhythmic, Cardiac Glycoside.
Afib & HF.
BBW: N/A

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12
Q

isosorbide dinitrate

A

Isordil.
Antianginal agent.
Angina prevention.
BBW: N/A

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13
Q

warfarin

A

Coumadin.
Vit K Antagonist.
Ppx and tx of thromboembolic disorders arising from afib/cardiac valve replacement; reduce risk of systemic embolism.
BBW: Bleeding risk

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14
Q

clopidogrel

A

Plavix.
Anti platelet Agent.
Unstable angina; NSTEMI; STEMI; recent MI/stroke; established PAD.
BBW: Increased levels in poor metabolizers (CYP 2C19)

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15
Q

enoxaparin

A

Lovenox.
LMWH.
Ppx and tx of DVT, unstable angina, NSTEMI, & STEMI.
BBW: Spinal/epidural hematomas

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16
Q

dabigatran

A

Pradaxa.
Thrombin Inhibitor.
Ppx of stroke & systemic embolism in patients with nonvalvular afib.
BBW: Discontinuing early inc risk of thrombotic event; spinal/epidural hematoma

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17
Q

rivaroxaban

A

Xarelto.
Factor Xa inhibitor.
Ppx of DVT in pts undergoing hip/knee replacement; prevention of stroke & systemic embolism in patients with nonvalvular afib; tx of acute PE & DVT without PE.
BBW: Discontinuing early inc risk of thrombotic event; spinal/epidural hematomas

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18
Q

amiodarone

A

Cordarone, Pacerone.
Antiarrhythmic Agent, Class III.
Ventricular arrythmias (vtach, vfib).
BBW: only for life-threatening arrhythmias, fatal toxicities, patients at high risk arrhythmic death

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19
Q

dofetilide

A

Tikosyn
Antiarrhythmic Agent, Class III
Mx of NSR in pts with chronic afib/a-flutter of longer than 1-week duration who have been converted to NSR; conversion of afib & a-flutter to NSR
BBW: should be placed for a minimum of 3 days in a facility that can provide calc of CrCl, continuous EKG monitoring, & cardiac resuscitation

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20
Q

alteplase

A

Activase.
Tissue plasminogen activator; fibrinolytic.
PE, STEMI, acute ischemic stroke.
BBW: N/A

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21
Q

calcium acetate

A

Phoslo.
Phosphate Binder.
Hyperphosphatemia in ESRD
BBW: N/A

22
Q

sevelamer

A

Renagel, Renvela.
Phosphate Binder.
Hyperphosphatemia in pts with CKD on hemodialysis
BBW: N/A

23
Q

midodrine

A

None.
α1 agonist.
Orthostatic hypotension.
BBW: can cause significant elevation of supine blood pressure, so only to be used in pts whose lives are considerably impaired despite std clinical care. Clinical benefits have not been verified

24
Q

epoetin alfa

A

Procrit, Epogen.
Colony Stimulating Factor; Erythropoiesis Stimulating Agent.
Anemia
BBW: inc CV events, tumor progression in cancer

25
Q

mycophenolate

A

CellCept.
Immunosuppressant.
Ppx of organ rejection kidney, liver, or heart transplants
BBW: malignancies/serious infection, experienced physician, fetal toxicity

26
Q

tacrolimus

A

Prograf.
Calcineurin Inhibitor.
Organ rejection in heart, kidney, & liver transplant
BBW: malignancies/serious infection, experienced physician

27
Q

cyclosporine

A

Neoral, Sandimmune.
Calcineurin Inhibitor .
Organ rejection ppx.
BBW: infections/malignancies, experienced physician, bioavailability different in modified vs. non-modified versions; absoprtion of Sandimmune is erratic so monitor drug levels

28
Q

alemtuzumab

A

Campath.
Anti-CD52 Antineoplastic Agent, mAb.
B-cell chronic lymphocytic leukemia; MS.
BBW: Bone marrow suppression, infusion reactions, infections

29
Q

quetiapine

A

Seroquel, Seroquel XR.
Atypical antipsychotic.
BPAD, major depressive disorder, schizo.
BBW: increased mortality in elderly patients with dementia-related psychosis; suicidal thoughts/behavior

30
Q

aripiprazole

A

Abilify.
Atypical antipsychotic.
Oral: BPAD, major depressive disorder, schizophrenia, Tourette’s. inject: schizo.
BBW: increased mortality in elderly patients with dementia-related psychosis; suicidality in children, adolescents, & young adults

31
Q

chlorpromazine

A

None.
Typical antipsychotic
Psychotic disorders, control N/V, acute intermittent porphyria.
BBW: increased mortality in elderly patients with dementia-related psychosis

32
Q

haloperidol

A

Haldol.
Typical antipsychotic.
Schizo, Tourette’s.
BBW: increased mortality in elderly patients with dementia-related psychosis

33
Q

venlafaxine

A

Effexor.
SNRI.
Major depressive disorder, GAD, social anxiety disorder, panic disorder
BBW: suicidality in children, adolescents, and young adults

34
Q

citalopram

A

Celexa.
SSRI.
Depression.
BBW: suicidality in children, adolescents, & young adults

35
Q

amitryptyline

A

Elavil.
TCA.
Depression.
BBW: Suicidality in children, adolescents, young adults

36
Q

bupropion

A

Wellbutrin.
DA/NE reuptake inhibitor.
Indication: depression, seasonal affective disorder; smoking cessation.
BBW: Suicidality in children, adolescents, & young adults, neuropsychiatric events in smoking cessation use

37
Q

trazodone

A

Oleptro.
Serotonin Reuptake Inhibitor/Antagonist.
Depression.
BBW: Suicidality & antidepressant drugs in children, adolescents, young adults

38
Q

alprazolam

A

Xanax.
Benzo.
Anxiety, GAD, panic disorder with or without agoraphobia; anxiety assoc with depression
BBW: N/A

39
Q

lorazepam

A

Ativan.
Benzo.
Anxiety, status epileptics.
BBW: N/A

40
Q

divalproex sodium

A

Depakote.
Anticonvulsant; Antimanic Agent.
Seizures; mania; migraine ppx.
BBW: Hepatotoxicity, mitochondrial disease, fetal risk, pancreatitis

41
Q

lamotrigine

A

Lamictal.
Anticonvulsant.
Seizures, bipolar 1 disorder.
BBW: Skin reactions

42
Q

pregabalin

A

Lyrics.
Anticonvulsant.
Neuropathic pain associated with DM or with spinal cord injury; postherpetic neuralgia; adj tx for partial-onset seizure disorder; fibromyalgia.
BBW: N/A

43
Q

sumatriptan

A

Imitrex.
Antimigraine Agent; 5HT 1B,1D Receptor Agonist.
Migraine with/without aura, cluster headache episodes.
BBW: N/A

44
Q

gabapentin

A

Neurontin.
Anticonvulsant (GABA analogue).
Seizures, postherpetic neuralgia.
BBW: n/a

45
Q

tramadol

A

Ultram.
Opioid analgesic.
Mod-to-severe pain.
BBW: n/a

46
Q

zolpidem

A

Ambien.
Non-barbiturate hypnotic.
Insomnia.
BBW: n/a

47
Q

methylphenidate

A

Ritalin, Concerta, Metadate, Daytrana (transdermal).
CNS Stimulant.
ADHD, narcolepsy.
BBW: Drug dependence

48
Q

amphetamine/dextroamphetamine

A

Adderall.
CNS Stimulant.
ADHD, narcolepsy.
BBW: drug dependence/abuse

49
Q

methadone

A

Dolophine.
Analgesic, Opioid.
Mod-to-severe pain when a cont, around-the-clock opioid analgesic is needed for an extended period of time; detox & mx tx of opioid addiction.
BBW: Abuse potential, respiratory depression, QT prolongation, accidental exposure may be fatal to children

50
Q

ropinirole

A

Requip.
Anti-Parkinson’s Agent, DA Agonist.
Parkinson’s; Restless Legs Syndrome.
BBW: n/a

51
Q

donepezil

A

Aricept.
Central AchE Inhibitor.
Alzheimer’s.
BBW: n/a