Spring Quiz 7

Question 1

Trazodone (Brand, Class, MOA)

Answer 1

Oleptro. Antidepressant, Serotonin Reuptake Inhibitor/Antagonist. Inhibits reuptake of serotonin, causes adrenoreceptor subsensitivity, and induces significant changes in 5-HT presynaptic receptor adrenoreceptors.

Question 2

Trazodone (Indication, BBW, Preg)

Answer 2

Depression. Suicidal thoughts and behaviors. No.

Question 3

Vilazodone (Brand, Class, MOA)

Answer 3

Viibryd. Antidepressant, Serotonin Reuptake Inhibitor/Antagonist. Vilazodone inhibits CNS neuron serotonin uptake, It also binds selectively with high affinity to 5-HT1A receptors and is a 5-HT1A receptor partial agonist.

Question 4

Vilazodone (Indication, BBW, Preg)

Answer 4

Depression. Suicidal thoughts and behaviors. No.

Question 5

Mirtazapine (Brand, Class, MOA)

Answer 5

Remeron, Remeron Soltab. Alpha-2 Adrenergic Antagonist, Antidepressant. Central presynaptic alpha2-antagonist effects, which results in increased release of NE and 5HT.

Question 6

Mirtazapine (Indication, BBW, Preg)

Answer 6

Major depressive disorder. Suicidal thoughts and behaviors. No.

Question 7

Alprazolam (Brand, Class, MOA)

Answer 7

Xanax. Benzo. Enhancement of the inhibitory effect of GABA on neuronal excitability results by increased neuronal membrane permeability to Cl ions. This shift in Cl ions results in hyperpolarization (a less excitable state) and stabilization.

Question 8

Alprazolam (Indication, BBW, Preg)

Answer 8

Panic and anxiety disorder. No. No.

Question 9

Lorazepam (Brand, Class, MOA)

Answer 9

Ativan. Benzo. Enhancement of the inhibitory effect of GABA on neuronal excitability results by increased neuronal membrane permeability to chloride ions. This shift in chloride ions results in hyperpolarization (a less excitable state) and stabilization.

Question 10

Lorazepam (Indication, BBW, Preg)

Answer 10

Anxiety, status elipticus. No. No.

Question 11

Divalproex sodium (Brand, Class, MOA)

Answer 11

Depakote. Anticonvulsant. Causes increased availability of GABA, an inhibitory NT, to brain neurons or may enhance the action of GABA or mimic its action at postsynaptic receptor sites.

Question 12

Divalproex sodium (Indication, BBW, Preg)

Answer 12

Seizures. Increased risk of acute liver failure, hepatotoxicity, fetal risk, and pancreatitis. X.

Question 13

Carbamazepine (Brand, Class, MOA)

Answer 13

Tegretol. Anticonvulsant. Anticholinergic, antineuralgic, antidiuretic, muscle relaxant, antimanic, antidepressive, and antiarrhythmic properties

Question 14

Carbamazepine (Indication, BBW, Preg)

Answer 14

Seizures. Toxic epidermal necrolysis, Stevens-Johnson Syndrome, Aplastic anema and agranulocytosis. No.

Question 15

Lamotrigine (Brand, Class, MOA)

Answer 15

Lamictal. Anticonvulsant. Anticholinergic, antineuralgic, antidiuretic, muscle relaxant, antimanic, antidepressive, and antiarrhythmic properties.

Question 16

Lamotrigine (Indication, BBW, Preg)

Answer 16

Seizures. Toxic epidermal necrolysis, Stevens-Johnson Syndrome, Aplastic anema and agranulocytosis. No.

Question 17

Lithium (Brand, Class, MOA)

Answer 17

Lithobid. Antimanic agent. Unknown.

Question 18

Lithium (Indication, BBW, Preg)

Answer 18

Bipolar disorder. Lithium toxicity is closely related to serum lithium levels, and can occur at doses close to therapeutic levels. No.

Question 19

Phenytoin (Brand, Class, MOA)

Answer 19

Dilantin. Anticonvulsant, hydantoin. Stabilizes neuronal membranes and decreases seizure activity by increasing efflux or decreasing influx of Na ions across cell membranes in the motor cortex during generation of nerve impulses.

Question 20

Phenytoin (Indication, BBW, Preg)

Answer 20

Seizures. Cardiovascular risk associated with rapid infusion. No.

Question 21

Pregabalin Brand, Class, MOA)

Answer 21

Lyrica. Anticonvulsant, analgesic. Binds to alpha2-delta subunit of voltage-gated Ca channels within the CNS and modulates Ca influx at the nerve terminals, thereby inhibiting excitatory NT release including glutamate, NE, 5HT, DA, substance P, and calcitonin gene-related peptide.

Question 22

Pregabalin (Indication, BBW, Preg)

Answer 22

Neuropathic pain, seizures. No. No.

Question 23

Sumatriptan (Brand, Class, MOA)

Answer 23

Imitrex. Serotonin R agonist. Selective agonist for serotonin on intracranial blood vessels and sensory nerves of the trigeminal system; causes vasoconstriction and reduces neurogenic inflammation associated with antidromic neuronal transmission correlating with relief of migraine

Question 24

Sumatriptan (Indication, BBW, Preg)

Answer 24

Migraine. No. No.